FPR2 and CAMP

Number of citations of the paper that reports this interaction (PMID 11015447)
176

Data Source:
HPRD (in vivo)

		FPR2	CAMP
Gene Name		formyl peptide receptor 2	cathelicidin antimicrobial peptide
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Space Cell Wall Cytosol Specific Granule Cell Projection Extracellular Vesicular Exosome
	Molecular Function	G-protein Coupled Receptor Activity N-formyl Peptide Receptor Activity	Protein Binding
	Biological Process	Movement Of Cell Or Subcellular Component Chemotaxis Inflammatory Response Cell Adhesion G-protein Coupled Receptor Signaling Pathway	Positive Regulation Of Protein Phosphorylation Innate Immune Response In Mucosa Positive Regulation Of Cell Proliferation Antibacterial Humoral Response Defense Response To Bacterium Negative Regulation Of Growth Of Symbiont In Host Negative Regulation Of Growth Of Symbiont On Or Near Host Surface Positive Regulation Of Angiogenesis Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Interaction With Host Killing By Host Of Symbiont Cells Cellular Response To Lipopolysaccharide Cellular Response To Peptidoglycan Cellular Response To Interleukin-1 Cellular Response To Interleukin-6 Cellular Response To Tumor Necrosis Factor Phagosome Maturation
Pathways		G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Class A/1 (Rhodopsin-like receptors) GPCR ligand binding Metabolic disorders of biological oxidation enzymes Formyl peptide receptors bind formyl peptides and many other ligands G alpha (q) signalling events GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK G alpha (i) signalling events	Phagosomal maturation (early endosomal stage) Latent infection of Homo sapiens with Mycobacterium tuberculosis
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: CAMP	6 interactors: CTSG ELANE FPR2 LBP MAPK8 PRTN3
Entrez ID		2358	820
HPRD ID		00647	02722
Ensembl ID		ENSG00000171049	ENSG00000164047
Uniprot IDs		P25090	J3KNB4 P49913
PDB IDs			2FBS 2FBU 2FCG 2K6O 2LMF 4EYC
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Growth Of Symbiont On Or Near Host Surface Sister Chromatid Biorientation Attachment Of Mitotic Spindle Microtubules To Kinetochore Cellular Response To Peptidoglycan Killing By Host Of Symbiont Cells Protein Localization To Microtubule Protein Localization To Kinetochore Protein Localization To Chromosome, Centromeric Region Attachment Of Spindle Microtubules To Kinetochore Response To Peptidoglycan Innate Immune Response In Mucosa Protein Localization To Cytoskeleton Killing Of Cells Of Other Organism Cellular Response To Interleukin-6 Negative Regulation Of Growth Of Symbiont In Host Antibacterial Humoral Response Mitotic Metaphase Plate Congression Antimicrobial Humoral Response Protein Localization To Chromosome Response To Interleukin-6 Metaphase Plate Congression Mucosal Immune Response Interaction With Symbiont Defense Response To Gram-negative Bacterium Establishment Of Chromosome Localization Phagosome Maturation Cellular Response To Interleukin-1 Microtubule Anchoring Defense Response To Gram-positive Bacterium Mitotic Sister Chromatid Segregation Response To Interleukin-1 Sister Chromatid Segregation Cellular Response To Tumor Necrosis Factor Interaction With Host Positive Regulation Of Angiogenesis Response To Tumor Necrosis Factor Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Defense Response To Bacterium Regulation Of Angiogenesis Chromosome Segregation Humoral Immune Response Negative Regulation Of Growth Response To Lipopolysaccharide Mitotic Nuclear Division Establishment Of Organelle Localization Response To Molecule Of Bacterial Origin	Negative Regulation Of Growth Of Symbiont In Host Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Killing By Host Of Symbiont Cells Response To Bacterium Defense Response Positive Regulation Of Immune Response Defense Response To Bacterium Response To Stress Neutrophil Mediated Immunity Response To Other Organism Response To Biotic Stimulus Killing Of Cells Of Other Organism Response To External Stimulus Defense Response To Fungus Negative Regulation Of Growth Response To Lipid Positive Regulation Of Interleukin-8 Production Regulation Of Immune Response Interaction With Symbiont Leukocyte Mediated Cytotoxicity Positive Regulation Of Immune System Process Immune System Process Response To Fungus Regulation Of Chemokine Production Collagen Catabolic Process Inflammatory Response Defense Response To Gram-positive Bacterium Positive Regulation Of Cytokine Biosynthetic Process Immune Response Regulation Of Immune System Process Acute Inflammatory Response Collagen Metabolic Process Toll-like Receptor 4 Signaling Pathway Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Toll-like Receptor Signaling Pathway Regulation Of Cytokine Biosynthetic Process Regulation Of Growth Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To UV Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Leukocyte Chemotaxis Involved In Inflammatory Response Lipopolysaccharide Transport Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Regulation Of Chemotaxis Activation Of Innate Immune Response
Tagcloud ?		amplified c5a c5ar chromosomes complement contained digestion electrophoresis filters formylpeptides fpr1 fprl2 fragment homologue hybridized il8ra il8rb kb kilobase library lie linkage mapped nylon probes pulsed restriction separated translated	2cl adh admittance antidiuretic ascending augment basolateral basolaterally bilayers channels cl clc conductance ctal cytosolic excised faces gate gated gating k1 ka microperfused mtal pka po rbclc rises thick threefold
Tagcloud (Difference) ?		amplified c5a c5ar chromosomes complement contained digestion electrophoresis filters formylpeptides fpr1 fprl2 fragment homologue hybridized il8ra il8rb kb kilobase library lie linkage mapped nylon probes pulsed restriction separated translated	2cl adh admittance antidiuretic ascending augment basolateral basolaterally bilayers channels cl clc conductance ctal cytosolic excised faces gate gated gating k1 ka microperfused mtal pka po rbclc rises thick threefold
Tagcloud (Intersection) ?