RBM22 and YBX2

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		RBM22	YBX2
Description		RNA binding motif protein 22	Y-box binding protein 2
Image
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding U6 SnRNA Binding Pre-mRNA Binding Metal Ion Binding Calcium-dependent Protein Binding	Nucleic Acid Binding DNA Binding RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of RNA Splicing Positive Regulation Of Protein Import Into Nucleus MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Protein Export From Nucleus Cellular Response To Xenobiotic Stimulus	Transcription By RNA Polymerase II Spermatogenesis Translational Attenuation Regulation Of Gene Expression Oocyte Development Positive Regulation Of Cold-induced Thermogenesis
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		45 interacting genes: AQR BAG4 BCAS2 BICD2 BMI1 CEBPA CEP55 CTBP1 CYSRT1 DMRTB1 EIF4ENIF1 ESS2 EXOSC7 EXOSC8 GIGYF1 GOLGA2 HNRNPUL1 HOMER3 HOOK1 KRT31 NCKIPSD NOA1 NXF1 OGT PQBP1 PRC1 PRMT2 PRNP PRPF39 PRPF6 RBFOX2 RBM4 RBPMS RNU6-1 RNU6-50P RNU6-6P SNRPA SNW1 TFIP11 TXNL4A VIM WBP4 YBX2 YTHDF1 YTHDF3	54 interacting genes: MIR1-1 MIR1-2 MIR106B MIR10B MIR128-1 MIR128-2 MIR138-2 MIR141 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR200A MIR200B MIR200C MIR205 MIR21 MIR214 MIR221 MIR222 MIR25 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-3 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCBP2 RBM22 SUPT5H TUT4
Entrez ID		55696	51087
HPRD ID		10186	18311
Ensembl ID		ENSG00000086589	ENSG00000006047
Uniprot IDs		Q9NW64	A0A384MDP4 Q9Y2T7
PDB IDs		2YTC 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P 7AAV 7ABG 7ABI 7QTT 7W59 7W5A 7W5B 8C6J 8CH6 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8RO2 9FMD	7F3I 7F3J 7F3K 7F3L
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Metabolic Process MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Spliceosomal Complex RNA Binding RNA Metabolic Process Catalytic Step 2 Spliceosome Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule MRNA Binding Nuclear Speck Nucleic Acid Metabolic Process U4/U6 X U5 Tri-snRNP Complex Membraneless Organelle Assembly U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Nucleus Identical Protein Binding Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleoplasm U2-type Catalytic Step 2 Spliceosome Cellular Component Assembly Exoribonuclease Complex Regulation Of RNA Splicing Nucleic Acid Binding P-body Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance Nuclear Polyadenylation-dependent RRNA Catabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Translational Initiation U4 SnRNA 3'-end Processing Regulation Of Long-term Synaptic Potentiation Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Translational Initiation Memory RRNA 3'-end Processing Nucleolar Exosome (RNase Complex) U2-type Precatalytic Spliceosome TRNA Decay Nuclear MRNA Surveillance Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Processing Pre-mRNA Intronic Binding	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Extracellular Vesicle Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Metabolic Process Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility MRNA Destabilization RNA Destabilization Negative Regulation Of Locomotion Positive Regulation Of MRNA Catabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Extracellular Space Positive Regulation Of MRNA Metabolic Process Regulation Of Endothelial Cell Migration Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Translation Regulation Of Connective Tissue Replacement Regulation Of MRNA Stability Regulation Of Cell Migration Regulation Of RNA Stability Regulation Of Cell Motility Negative Regulation Of Multicellular Organismal Process Regulation Of Locomotion Negative Regulation Of Protein Metabolic Process Positive Regulation Of Tissue Remodeling
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?