SLC16A8 and RAB1A

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SLC16A8	RAB1A
Gene Name		solute carrier family 16 (monocarboxylate transporter), member 8	RAB1A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane	Golgi Membrane Early Endosome Endoplasmic Reticulum Membrane Cytosol Melanosome Extracellular Vesicular Exosome
	Molecular Function	Lactate Transmembrane Transporter Activity Symporter Activity Secondary Active Monocarboxylate Transmembrane Transporter Activity	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Pyruvate Metabolic Process Blood Coagulation Lactate Transport Plasma Membrane Lactate Transport Cellular Metabolic Process Small Molecule Metabolic Process Leukocyte Migration Transmembrane Transport	Autophagic Vacuole Assembly Mitotic Cell Cycle Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Endocytosis Autophagy Golgi Organization Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Rab Protein Signal Transduction Substrate Adhesion-dependent Cell Spreading Cilium Assembly Defense Response To Bacterium Vesicle Transport Along Microtubule Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process
Pathways		Pyruvate metabolism Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Proton-coupled monocarboxylate transport SLC-mediated transmembrane transport Basigin interactions Cell surface interactions at the vascular wall	Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs		Pyruvic acid
Diseases
GWAS		Age-related macular degeneration ( 23455636)
Protein-Protein Interactions		2 interactors: DNAJB9 RAB1A	28 interactors: ADCK1 CAPNS1 CDKN1A CHM CHML CREB1 FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 OCRL PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RABIF RFK RUSC2 SLC16A8 SYT5 TBC1D17 USO1 ZNF593
Entrez ID		23539	5861
HPRD ID		11568	01538
Ensembl ID		ENSG00000100156	ENSG00000138069
Uniprot IDs		O95907	B7Z8M7 P62820 Q5U0I6
PDB IDs			2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS
Enriched GO Terms of Interacting Partners?		Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Interleukin-8 Production Cargo Loading Into Vesicle Growth Hormone Secretion Positive Regulation Of Glycoprotein Metabolic Process COPII-coated Vesicle Budding Virion Assembly Positive Regulation Of Protein Metabolic Process Cytokine Secretion Vesicle Transport Along Microtubule Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization ER-associated Ubiquitin-dependent Protein Catabolic Process Localization Within Membrane Melanosome Localization Autophagic Vacuole Assembly Substrate Adhesion-dependent Cell Spreading Cellular Response To Stress Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Organelle Transport Along Microtubule Macroautophagy Rab Protein Signal Transduction Cellular Pigmentation Peptide Hormone Secretion Peptide Secretion Catabolic Process Golgi Organization Membrane Budding Hormone Secretion Endoplasmic Reticulum Unfolded Protein Response Hormone Transport Peptide Transport Cellular Response To Unfolded Protein ER To Golgi Vesicle-mediated Transport Regulation Of Protein Metabolic Process Vacuole Organization ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Pigmentation Protein Secretion Amide Transport Response To Unfolded Protein Microtubule-based Transport Cytokine Production Cellular Response To Starvation Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Cellular Metabolic Process	Protein Geranylgeranylation Protein Prenylation Positive Regulation Of Catalytic Activity Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Membrane Fusion Positive Regulation Of Metabolic Process Protein Transport Establishment Of Protein Localization Visual Perception Sensory Perception Of Light Stimulus Slow Endocytic Recycling Riboflavin Biosynthetic Process FMN Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Membrane Organization Positive Regulation Of Microtubule Plus-end Binding Golgi Vesicle Docking Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cell Cycle Positive Regulation Of Cell Cycle Arrest Cellular Process Positive Regulation Of NAD(P)H Oxidase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle Apoptotic Process Protein Localization Vesicle-mediated Transport Programmed Cell Death Signal Transduction In Response To DNA Damage Establishment Of Localization In Cell Mitotic DNA Damage Checkpoint Cell Death Death Intestinal Epithelial Cell Maturation Riboflavin Metabolic Process Regulation Of Cell Cycle Arrest Intracellular Transport Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint
Tagcloud ?			added become broadly characterises eevs enveloped exploits facilitating golgi growing gtpase highlighting ievs immunofluorescence imvs list maintenance mature numerous optimal proviral refined replication require stranded vaccinia vacv virions wrapping
Tagcloud (Difference) ?			added become broadly characterises eevs enveloped exploits facilitating golgi growing gtpase highlighting ievs immunofluorescence imvs list maintenance mature numerous optimal proviral refined replication require stranded vaccinia vacv virions wrapping
Tagcloud (Intersection) ?