SLC16A8

Gene Name		solute carrier family 16 (monocarboxylate transporter), member 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Lactate Transmembrane Transporter Activity Symporter Activity Secondary Active Monocarboxylate Transmembrane Transporter Activity
	Biological Process	Pyruvate Metabolic Process Blood Coagulation Lactate Transport Plasma Membrane Lactate Transport Cellular Metabolic Process Small Molecule Metabolic Process Leukocyte Migration Transmembrane Transport
Pathways		Pyruvate metabolism Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Proton-coupled monocarboxylate transport SLC-mediated transmembrane transport Basigin interactions Cell surface interactions at the vascular wall
Drugs		Pyruvic acid
Diseases
GWAS		Age-related macular degeneration ( 23455636)
Protein-protein Interactions		2 interactors: DNAJB9 RAB1A
Entrez ID		23539
HPRD ID		11568
Ensembl ID		ENSG00000100156
Uniprot IDs		O95907
PDB IDs
Enriched GO Terms of Interacting Partners?		Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Interleukin-8 Production Cargo Loading Into Vesicle Growth Hormone Secretion Positive Regulation Of Glycoprotein Metabolic Process COPII-coated Vesicle Budding Virion Assembly Positive Regulation Of Protein Metabolic Process Cytokine Secretion Vesicle Transport Along Microtubule Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization ER-associated Ubiquitin-dependent Protein Catabolic Process Localization Within Membrane Melanosome Localization Autophagic Vacuole Assembly Substrate Adhesion-dependent Cell Spreading Cellular Response To Stress Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Organelle Transport Along Microtubule Macroautophagy Rab Protein Signal Transduction Cellular Pigmentation Peptide Hormone Secretion Peptide Secretion Catabolic Process Golgi Organization Membrane Budding Hormone Secretion Endoplasmic Reticulum Unfolded Protein Response Hormone Transport Peptide Transport Cellular Response To Unfolded Protein ER To Golgi Vesicle-mediated Transport Regulation Of Protein Metabolic Process Vacuole Organization ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Pigmentation Protein Secretion Amide Transport Response To Unfolded Protein Microtubule-based Transport Cytokine Production Cellular Response To Starvation Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Cellular Metabolic Process
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