SLC16A8

Description		solute carrier family 16 member 8
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Apical Part Of Cell
	Molecular Function	Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Symporter Activity Transmembrane Transporter Activity
	Biological Process	Monocarboxylic Acid Transport Lactate Transport Lactate Transmembrane Transport Transmembrane Transport
Pathways		Basigin interactions Proton-coupled monocarboxylate transport
Drugs		Pyruvic acid
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 23455636) Brain morphology (MOSTest) ( 32665545) Glioblastoma ( 28346443) Glioma ( 28346443)
Interacting Genes		2 interacting genes: DNAJB9 RAB1A
Entrez ID		23539
HPRD ID		11568
Ensembl ID		ENSG00000100156
Uniprot IDs		O95907
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of IRE1-mediated Unfolded Protein Response Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Misfolded Protein Binding Negative Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of Glycoprotein Metabolic Process Pigment Granule Localization Establishment Of Melanosome Localization Establishment Of Endothelial Intestinal Barrier Melanosome Localization COPII-coated Vesicle Cargo Loading Melanosome Transport Pigment Granule Transport Growth Hormone Secretion Virion Assembly Vesicle Cargo Loading Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Gene Expression Hsp70 Protein Binding Negative Regulation Of Response To Endoplasmic Reticulum Stress Vesicle Transport Along Microtubule Substrate Adhesion-dependent Cell Spreading Endothelial Cell Development Establishment Of Endothelial Barrier Transport Vesicle Membrane
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