FOS and MAFF

Number of citations of the paper that reports this interaction (PMID 23661758)
2

Data Source:
BioGRID (fluorescent resonance energy transfer)

		FOS	MAFF
Gene Name		FBJ murine osteosarcoma viral oncogene homolog	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Endoplasmic Reticulum Cytosol Membrane Neuron Projection	Nucleoplasm
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Transcription Regulatory Region DNA Binding R-SMAD Binding	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Conditioned Taste Aversion Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway DNA Methylation Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Inflammatory Response Transforming Growth Factor Beta Receptor Signaling Pathway Nervous System Development Female Pregnancy Aging Response To Cold Response To Light Stimulus Response To Mechanical Stimulus Response To Gravity Response To Toxic Substance Sleep Cellular Response To Extracellular Stimulus Response To Lipopolysaccharide Response To Progesterone Cellular Response To Hormone Stimulus Response To Cytokine Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Cellular Response To Reactive Oxygen Species TRIF-dependent Toll-like Receptor Signaling Pathway Response To Immobilization Stress Skeletal Muscle Cell Differentiation Fc-epsilon Receptor Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Response To Drug Innate Immune Response Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Stress-activated MAPK Cascade Response To Corticosterone Response To CAMP SMAD Protein Signal Transduction Cellular Response To Calcium Ion	In Utero Embryonic Development Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Parturition Blood Coagulation Skeletal Muscle Cell Differentiation Regulation Of Epidermal Cell Differentiation
Pathways		Toll Like Receptor 7/8 (TLR7/8) Cascade Cellular Senescence FCERI mediated MAPK activation Toll Like Receptor TLR6:TLR2 Cascade Activated TLR4 signalling Toll Like Receptor TLR1:TLR2 Cascade Activation of the AP-1 family of transcription factors MyD88 cascade initiated on plasma membrane Toll Like Receptor 5 (TLR5) Cascade MyD88 dependent cascade initiated on endosome TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88:Mal cascade initiated on plasma membrane Toll Like Receptor 9 (TLR9) Cascade Innate Immune System TRIF-mediated TLR3/TLR4 signaling MAP kinase activation in TLR cascade Senescence-Associated Secretory Phenotype (SASP) MyD88-independent cascade Toll Like Receptor 2 (TLR2) Cascade Toll-Like Receptors Cascades Toll Like Receptor 10 (TLR10) Cascade Oxidative Stress Induced Senescence Toll Like Receptor 3 (TLR3) Cascade Toll Like Receptor 4 (TLR4) Cascade Fc epsilon receptor (FCERI) signaling MAPK targets/ Nuclear events mediated by MAP kinases	Factors involved in megakaryocyte development and platelet production
Drugs		Nadroparin
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Periodontal microbiota ( 22699663)
Protein-Protein Interactions		108 interactors: ANP32E APP AQP1 ARFGAP1 ARL6IP4 ATF2 ATF3 ATF4 ATF7 ATP5I BATF BCL3 CABP1 CARM1 CEBPA CEBPE CEBPG CENPO CFAP57 CLU COPS4 CREB5 CREBBP CSNK2A1 CSNK2A2 CYTH4 DDIT3 EEF1D ELK1 ELK4 EPHB2 ETS1 ETS2 GAMT GATA4 GLB1 GNG11 GRHPR GTF2E2 GTF2F1 GTF2F2 HNF1A HSPA1A JUN JUNB JUND KDM2A LMNA LMO3 LUZP4 MAF MAFB MAFF MAP1B MAP3K7 MAPK1 MAPK7 MITF MTERF4 NACA NCOA1 NCOA2 NCOA3 NCOA6 NCOR2 NEFM NELFB NFATC3 NFKB1 OPTN PML POLR2E PRKAA2 PRKACA PSMC5 RB1 RELA RPS6KA1 RPS6KA2 RPS6KA4 RUNX1 RUNX2 SCHIP1 SET SIRT1 SMAD3 SMARCD1 SPI1 SRA1 STAT1 SUMO1 SUMO2 SUMO3 SUMO4 TAF1 TBP TRO TSC22D3 TSPAN2 UBE2D1 UBE2I UBE2L3 UBR1 USF1 USF2 VDR XBP1 ZNF133	23 interactors: ATF3 BACH1 BACH2 BATF2 BATF3 DDIT3 FOS GTF2A1L HDAC5 HOXD12 MAFG MAFIP NFE2 NFE2L1 NFE2L2 NFE2L3 NFIL3 NR3C1 NRF1 OVOL1 PPARG PRRX1 PSAP
Entrez ID		2353	23764
HPRD ID		01275	05343
Ensembl ID		ENSG00000170345	ENSG00000185022
Uniprot IDs		B4DQ65 P01100 Q6FG41	Q9ULX9
PDB IDs		1A02 1FOS 1S9K
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Gene Expression Gene Expression RNA Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Differentiation Negative Regulation Of Biosynthetic Process Response To Organic Substance Negative Regulation Of Gene Expression Regulation Of Cellular Process Cellular Response To Organic Substance Developmental Process System Development Viral Process Anatomical Structure Development Cell Differentiation Response To Stress Multicellular Organismal Development Response To External Stimulus Organ Development Negative Regulation Of Transcription From RNA Polymerase II Promoter TRIF-dependent Toll-like Receptor Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Regulation Of Cellular Process Multicellular Organismal Development System Development Anatomical Structure Development Organ Development Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Developmental Process Positive Regulation Of Metabolic Process Response To Stress Myeloid Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Hemopoiesis Cellular Response To Oxidative Stress Cellular Response To Organic Substance Immune System Development
Tagcloud ?		ap argue capable dimeric dimerization disrupt glucocorticoid heterodimerization homo homodimerization hraralpha hybrid indirect interfere jun liganded occurring promoters protooncoproteins ra raralpha rars repress repression responsive retinoic retinoid rxr rxrs	albeit arrested asymmetric constitute dimerizes dissect e2 erythroid heterodimeric lineages livers mafg mafk megakaryocyte megakaryocytes megakaryocytic mpl nucleotides outside p18 p45 polypeptides predominate profound rarity readily recognizes thrombocytopenia
Tagcloud (Difference) ?		ap argue capable dimeric dimerization disrupt glucocorticoid heterodimerization homo homodimerization hraralpha hybrid indirect interfere jun liganded occurring promoters protooncoproteins ra raralpha rars repress repression responsive retinoic retinoid rxr rxrs	albeit arrested asymmetric constitute dimerizes dissect e2 erythroid heterodimeric lineages livers mafg mafk megakaryocyte megakaryocytes megakaryocytic mpl nucleotides outside p18 p45 polypeptides predominate profound rarity readily recognizes thrombocytopenia
Tagcloud (Intersection) ?