MAFF and BATF2

Number of citations of the paper that reports this interaction (PubMedID 23661758)
48

Data Source:
BioGRID (fluorescent resonance energy transfer)

		MAFF	BATF2
Description		MAF bZIP transcription factor F	basic leucine zipper ATF-like transcription factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion RNA Polymerase II Transcription Regulator Complex	Chromatin Nucleus RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Parturition Skeletal Muscle Cell Differentiation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation Defense Response To Protozoan Myeloid Dendritic Cell Differentiation Integrated Stress Response Signaling
Pathways		Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Birth weight ( 31043758) Estimated glomerular filtration rate ( 31451708 31152163 31015462) Estimated glomerular filtration rate in non-diabetics ( 31451708) Fasting plasma glucose ( 32902719) HDL cholesterol ( 30275531) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Height ( 31562340) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) Liver enzyme levels (alanine transaminase) ( 33972514) Red blood cell count ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 32154731 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		20 interacting genes: ATF3 BACH2 BATF2 BATF3 DDIT3 FOS GTF2A1L HDAC5 HOXD12 MAFIP NFE2 NFE2L1 NFE2L2 NFIL3 NR3C1 NRF1 OVOL1 PPARG PRRX1 PSAP	29 interacting genes: AKAP19 ATF4 ATXN1 BACH1 CEBPA CEBPE CEBPG DAZAP2 DBP DDIT3 DEDD EPAS1 FOXH1 FOXI1 GPSM3 HLA-C HOXA1 JUN JUNB KAT2A KRT34 MAFF MKRN3 PPP1R16A PROP1 RELA SPAG8 VENTX YTHDF1
Entrez ID		23764	116071
HPRD ID		05343	14470
Ensembl ID		ENSG00000185022	ENSG00000168062
Uniprot IDs		Q9ULX9	B4DV37 Q8N1L9
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulator Complex DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity DNA Binding Chromatin Integrated Stress Response Signaling DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Nucleus Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Mononuclear Cell Differentiation Negative Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Sequence-specific Double-stranded DNA Binding Protein-DNA Complex Leukocyte Differentiation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Myeloid Cell Differentiation Regulation Of Macromolecule Metabolic Process Transcription Cis-regulatory Region Binding Positive Regulation Of Transcription By RNA Polymerase II Myeloid Leukocyte Differentiation Positive Regulation Of Macromolecule Biosynthetic Process CHOP-ATF3 Complex Positive Regulation Of Biosynthetic Process Identical Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Cell Redox Homeostasis Transcription Coregulator Binding Negative Regulation Of Biosynthetic Process Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Metabolic Process	DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Integrated Stress Response Signaling RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Regulator Complex Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Sequence-specific Double-stranded DNA Binding Sequence-specific DNA Binding DNA-binding Transcription Factor Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Transcription Cis-regulatory Region Binding Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Liver Development General Transcription Initiation Factor Binding Negative Regulation Of RNA Metabolic Process Developmental Process CHOP-ATF4 Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Myeloid Cell Differentiation Nucleus Gland Development DNA-templated Transcription CHOP-C/EBP Complex Cell Differentiation Animal Organ Development RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Macromolecule Biosynthetic Process
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