SRRM2 and TTC14

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		SRRM2	TTC14
Gene Name		serine/arginine repetitive matrix 2	tetratricopeptide repeat domain 14
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome
	Molecular Function	Poly(A) RNA Binding Protein N-terminus Binding C2H2 Zinc Finger Domain Binding	Nucleic Acid Binding
	Biological Process	MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: APP CSNK2A1 PIN1 PNN PRPF6 SNIP1 SRRM1 SRSF4 TTC14 XRN1 YWHAB YWHAG	11 interactors: CCDC85B CHERP DGCR14 FRA10AC1 IK NKAP RBM39 SF3B2 SNIP1 SNW1 SRRM2
Entrez ID		23524	151613
HPRD ID		06913	15579
Ensembl ID		ENSG00000167978	ENSG00000163728
Uniprot IDs		Q9UQ35	Q69YS0 Q86TA5 Q96N46
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process RNA Processing MRNA Processing Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA 3'-end Processing RNA Metabolic Process RNA Splicing RNA 3'-end Processing RNA Localization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Mitochondrion Organization Cellular Nitrogen Compound Metabolic Process Intracellular Transport Negative Regulation Of Cellular Protein Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination Negative Regulation Of Protein Metabolic Process RNA Export From Nucleus Regulation Of Organelle Organization Axon Guidance Nitrogen Compound Metabolic Process Apoptotic Process Regulation Of Mitotic Cell Cycle Programmed Cell Death Regulation Of Mitochondrion Organization Regulation Of Metabolic Process Synaptic Growth At Neuromuscular Junction Cell Death Death Regulation Of Protein Phosphorylation Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Process Establishment Of Localization In Cell Regulation Of RNA Metabolic Process Nuclear Export MRNA Transport Cellular Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Mitotic Nuclear Division Axonogenesis Positive Regulation Of Protein Metabolic Process	RNA Processing RNA Metabolic Process RNA Splicing Gene Expression MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Vitamin D Receptor Signaling Pathway Negative Regulation Of Gene Expression Notch Signaling Pathway Regulation Of Vitamin D Receptor Signaling Pathway Cellular Metabolic Process Positive Regulation Of NFAT Protein Import Into Nucleus Positive Regulation By Host Of Viral Transcription
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