SRRM2 and SRSF4

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SRRM2	SRSF4
Gene Name		serine/arginine repetitive matrix 2	serine/arginine-rich splicing factor 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Poly(A) RNA Binding Protein N-terminus Binding C2H2 Zinc Finger Domain Binding	Nucleotide Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Hematopoietic Progenitor Cell Differentiation Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: APP CSNK2A1 PIN1 PNN PRPF6 SNIP1 SRRM1 SRSF4 TTC14 XRN1 YWHAB YWHAG	23 interactors: DYRK1A FUS GEMIN2 HAP1 HTATSF1 PNN PPARGC1A PRPF38A RNPS1 SART1 SCAF11 SMURF1 SMURF2 SREK1 SRPK1 SRRM2 SRSF1 SRSF10 SRSF2 SRSF6 TICAM1 TRA2B ZDHHC17
Entrez ID		23524	6429
HPRD ID		06913	09052
Ensembl ID		ENSG00000167978	ENSG00000116350
Uniprot IDs		Q9UQ35	Q08170
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process RNA Processing MRNA Processing Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA 3'-end Processing RNA Metabolic Process RNA Splicing RNA 3'-end Processing RNA Localization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Mitochondrion Organization Cellular Nitrogen Compound Metabolic Process Intracellular Transport Negative Regulation Of Cellular Protein Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination Negative Regulation Of Protein Metabolic Process RNA Export From Nucleus Regulation Of Organelle Organization Axon Guidance Nitrogen Compound Metabolic Process Apoptotic Process Regulation Of Mitotic Cell Cycle Programmed Cell Death Regulation Of Mitochondrion Organization Regulation Of Metabolic Process Synaptic Growth At Neuromuscular Junction Cell Death Death Regulation Of Protein Phosphorylation Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Process Establishment Of Localization In Cell Regulation Of RNA Metabolic Process Nuclear Export MRNA Transport Cellular Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Mitotic Nuclear Division Axonogenesis Positive Regulation Of Protein Metabolic Process	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Gene Expression Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nuclear Export Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus RNA Export From Nucleus Regulation Of Alternative MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Assembly Termination Of RNA Polymerase II Transcription MRNA Transport Cellular Metabolic Process Nucleocytoplasmic Transport Nuclear Transport RNA Transport RNA Localization Ribonucleoprotein Complex Biogenesis Negative Regulation Of MRNA Splicing, Via Spliceosome DNA-templated Transcription, Termination Negative Regulation Of RNA Splicing MRNA 3'-end Processing Regulation Of RNA Metabolic Process RNA 3'-end Processing Regulation Of Nitrogen Compound Metabolic Process Spliceosomal SnRNP Assembly MRNA Splice Site Selection Ubiquitin-dependent SMAD Protein Catabolic Process Cellular Macromolecular Complex Assembly Regulation Of Gene Expression Cytoplasmic Transport Metabolic Process MRNA Cis Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Intracellular Transport Regulation Of Metabolic Process
Tagcloud ?			abundant altering changed clk decay deep detained detention dis dramatic evolutionarily half hour intron introns lives mdm4 nmd nonsense polyadenylated pools shift splicing subject thousands transcript triggered undergoes widespread
Tagcloud (Difference) ?			abundant altering changed clk decay deep detained detention dis dramatic evolutionarily half hour intron introns lives mdm4 nmd nonsense polyadenylated pools shift splicing subject thousands transcript triggered undergoes widespread
Tagcloud (Intersection) ?