U2SURP and DDX42

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		U2SURP	DDX42
Gene Name		U2 snRNP-associated SURP domain containing	DEAD (Asp-Glu-Ala-Asp) box helicase 42
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Cajal Body Membrane Nuclear Speck
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding	Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	RNA Processing	Protein Localization Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CTNNBL1 DDX42 PRPF40A RBM17 TBC1D4 TERT TRA2A	10 interactors: APP DHX15 FBXO25 PRPF19 RECQL5 SF3A1 SF3B4 SNRPC U2SURP UBC
Entrez ID		23350	11325
HPRD ID		19056	09909
Ensembl ID		ENSG00000163714	ENSG00000198231
Uniprot IDs		O15042	Q86XP3
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Production Of SiRNA Involved In RNA Interference Negative Regulation Of RNA Interference Transcription, RNA-templated RNA Metabolic Process Telomere Formation Via Telomerase Age-dependent Telomere Shortening Gene Expression Telomere Maintenance Via Telomere Shortening Telomere Assembly Negative Regulation Of Vesicle Fusion Replicative Cell Aging Telomere Maintenance Via Telomerase Production Of SiRNA Involved In RNA Interference Nucleobase-containing Compound Metabolic Process RNA Interference Alternative MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Replicative Senescence Cellular Nitrogen Compound Metabolic Process RNA-dependent DNA Replication Regulation Of Gene Silencing DNA Strand Elongation Nitrogen Compound Metabolic Process Telomere Maintenance Via Telomere Lengthening Cellular Response To DsRNA Regulation Of Vesicle Fusion Somatic Diversification Of Immunoglobulins Posttranscriptional Gene Silencing	RNA Processing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Splicing Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Regulation Of Cell Cycle Phase Transition Spliceosomal SnRNP Assembly Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway MRNA Splice Site Selection Cellular Metabolic Process Ribonucleoprotein Complex Biogenesis Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Generation Of Catalytic Spliceosome For First Transesterification Step Regulation Of ERBB Signaling Pathway Regulation Of MRNA Processing Signal Transduction In Response To DNA Damage Regulation Of RNA Splicing Synaptic Growth At Neuromuscular Junction Regulation Of Cell Cycle Process Collateral Sprouting In Absence Of Injury Protein Ubiquitination Notch Signaling Pathway MRNA 5'-splice Site Recognition DNA Repair Protein Modification By Small Protein Conjugation DNA Damage Checkpoint Cellular Macromolecular Complex Assembly Collateral Sprouting Axon Midline Choice Point Recognition MRNA 3'-splice Site Recognition Protein Polyubiquitination Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Gene Expression Axon Choice Point Recognition Negative Regulation Of Neuron Differentiation
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