CSTF2T and COL17A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CSTF2T	COL17A1
Description		cleavage stimulation factor subunit 2 tau variant	collagen type XVII alpha 1 chain
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex	Extracellular Region Collagen Trimer Basement Membrane Endoplasmic Reticulum Lumen Plasma Membrane Cell-cell Junction Membrane Hemidesmosome Extracellular Matrix Anchoring Junction
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	MRNA Processing MRNA 3'-end Processing	Cell-matrix Adhesion Epidermis Development Hemidesmosome Assembly
Pathways		mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	Collagen degradation Collagen biosynthesis and modifying enzymes Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly Collagen chain trimerization
Drugs
Diseases			Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS		Interferon alpha levels in systemic lupus erythematosus ( 25338677) Logical memory (delayed recall) in normal cognition ( 29274321) Mammographic density (non-dense area) ( 25342443)	Cardiac hypertrophy ( 21348951)
Interacting Genes		23 interacting genes: AKAP8L ATP23 CDSN COL17A1 CPSF1 CRYAA CTAG1A CTAG1B CTDSP1 FAM168B FOXI1 FOXJ2 GOLGA2 HGS LASP1 PKNOX2 SMYD3 SPAG8 STH TLE5 TOX2 UBQLN1 UBQLN4	18 interacting genes: ACTN1 ACTN4 CLSTN1 CSTF2T CTNND1 DSP DST ITGA6 ITGB4 KRT18 LAD1 PLEC PLOD3 PNKP PPIL1 PPL UBQLN2 WHRN
Entrez ID		23283	1308
HPRD ID		09900	00223
Ensembl ID		ENSG00000177613	ENSG00000065618
Uniprot IDs		Q9H0L4	Q9UMD9
PDB IDs			8IZS
Enriched GO Terms of Interacting Partners?			Cell-substrate Junction Organization Cell-substrate Junction Assembly Anchoring Junction Hemidesmosome Assembly Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Hemidesmosome Cell Junction Organization Cell-cell Adhesion Intermediate Filament Structural Molecule Activity Wound Healing Cell Adhesion Response To Wounding Focal Adhesion Cell Junction Assembly Extracellular Exosome Z Disc Neuregulin Binding Integrin Binding Cadherin Binding Nail Development Fascia Adherens Cytoskeleton Organization Skin Morphogenesis Insulin-like Growth Factor I Binding Stress Fiber Basement Membrane Muscle Cell Development Pseudopodium Cell Periphery Integrin-mediated Signaling Pathway Structural Constituent Of Cytoskeleton Myelination In Peripheral Nervous System Actin Cytoskeleton Integrin Complex Plasma Membrane Cytoskeleton Anatomical Structure Morphogenesis Desmosome Actin Binding Cell-cell Junction Organization Cell Morphogenesis Adherens Junction Negative Regulation Of Blood Vessel Branching Integrin Alpha6-beta4 Complex X11-like Protein Binding Actin Filament Binding Cell Junction Cell-cell Junction
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