COL17A1 and CTNND1

Number of citations of the paper that reports this interaction (PMID 10321838)
5

Data Source:
HPRD (in vitro, two hybrid)

		COL17A1	CTNND1
Gene Name		collagen, type XVII, alpha 1	catenin (cadherin-associated protein), delta 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Trimer Basement Membrane Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Hemidesmosome	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Zonula Adherens Lamellipodium Growth Cone Midbody Dendritic Spine Synapse Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Receptor Binding Protein Binding Protein Kinase Binding Cadherin Binding
	Biological Process	Cell-matrix Adhesion Epidermis Development Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Hemidesmosome Assembly Cell Junction Assembly	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Adhesion Brain Development Wnt Signaling Pathway Single Organismal Cell-cell Adhesion Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Cell junction organization Type I hemidesmosome assembly Collagen formation Collagen degradation Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures	Cell junction organization Cell-cell junction organization Signaling by VEGF Adherens junctions interactions VEGFR2 mediated vascular permeability VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951)
Protein-Protein Interactions		12 interactors: ACTN1 ACTN4 CLSTN1 CTNND1 DSP DST ITGA6 ITGB4 KRT18 LAD1 PLEC PPL	26 interactors: ACTA1 APP CDH1 CDH24 CDH3 CDH5 COL17A1 CTTN EGFR ERBB2IP FER GRIK2 GSK3B JUP KCTD6 LCK MTNR1B MUC1 PSEN1 PTPN6 PTPRJ PTPRM SNCA SRC YWHAG ZBTB33
Entrez ID		1308	1500
HPRD ID		00223	03026
Ensembl ID		ENSG00000065618	ENSG00000198561
Uniprot IDs		Q9UMD9	C9JZR2 O60716
PDB IDs			3L6X 3L6Y
Enriched GO Terms of Interacting Partners?		Cell Junction Assembly Hemidesmosome Assembly Cell-substrate Junction Assembly Protein Localization To Cell Junction Protein Localization To Tight Junction Cell Adhesion Response To Wounding Extracellular Matrix Organization Extracellular Structure Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cell-cell Junction Organization Skin Development Cellular Component Assembly Nail Development Adherens Junction Organization Integrin-mediated Signaling Pathway Amelogenesis Actin Crosslink Formation Filopodium Assembly Cell-matrix Adhesion Cytoskeleton Organization Cell-substrate Adhesion Wound Healing Tight Junction Assembly Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Actin Filament Bundle Assembly Platelet Degranulation Golgi To Plasma Membrane CFTR Protein Transport Apical Junction Assembly Execution Phase Of Apoptosis Keratinocyte Differentiation Blood Coagulation Hemostasis Ventricular Compact Myocardium Morphogenesis Odontogenesis Of Dentin-containing Tooth Cell-cell Junction Assembly Positive Regulation Of Pinocytosis Single Organismal Cell-cell Adhesion Odontogenesis Positive Regulation Of Sodium:proton Antiporter Activity Protein Localization To Adherens Junction Epidermal Cell Differentiation Digestive Tract Development Regulation Of Body Fluid Levels Digestive System Development Response To Stress Regulation Of Sodium:proton Antiporter Activity Ectodermal Cell Differentiation Peroxisome Proliferator Activated Receptor Signaling Pathway	Cell Adhesion Adherens Junction Organization Regulation Of Signaling Single Organismal Cell-cell Adhesion Regulation Of Signal Transduction Regulation Of Cellular Localization Regulation Of Intracellular Transport Cellular Response To Organonitrogen Compound Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Junction Assembly Cell-cell Junction Organization Locomotion Cellular Response To Stimulus Regulation Of Phosphorylation Regulation Of Protein Phosphorylation Regulation Of Cellular Amino Acid Metabolic Process Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Negative Regulation Of Protein Metabolic Process Signaling Negative Regulation Of Signaling Enzyme Linked Receptor Protein Signaling Pathway Cell Communication Regulation Of ERBB Signaling Pathway Regulation Of Cellular Protein Metabolic Process Apoptotic Process Regulation Of Cellular Ketone Metabolic Process Signal Transduction Regulation Of Protein Kinase Activity Response To Drug Programmed Cell Death Cell Death Death Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Developmental Process Negative Regulation Of Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Response To Mechanical Stimulus Anatomical Structure Development Response To Organonitrogen Compound Response To External Stimulus Regulation Of Apoptotic Process Cell Migration Regulation Of Cell Proliferation Positive Regulation Of Intracellular Transport
Tagcloud ?		aligning alopecia atrophic blistering bullosa codons corrective correlating dystrophy enamel epidermolysis exons faulty harbouring herlitz hypoplasia introns jeb junctional milder mucous nail nh nonsense pitting premtrna repaired vicinity xvii	abi1 atlas bitbucket ccnd3 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf myh11 org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript
Tagcloud (Difference) ?		aligning alopecia atrophic blistering bullosa codons corrective correlating dystrophy enamel epidermolysis exons faulty harbouring herlitz hypoplasia introns jeb junctional milder mucous nail nh nonsense pitting premtrna repaired vicinity xvii	abi1 atlas bitbucket ccnd3 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf myh11 org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript
Tagcloud (Intersection) ?