PDS5A and WAPAL

Number of citations of the paper that reports this interaction (PMID 21111234)
42

Data Source:
BioGRID (pull down)

		PDS5A	WAPAL
Gene Name		PDS5 cohesin associated factor A	wings apart-like homolog (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleoplasm Chromosome Cytosol Plasma Membrane	Chromosome, Centromeric Region Chromatin Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Cohesin Complex Microtubule Cytoskeleton Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Mitotic Sister Chromatid Cohesion Negative Regulation Of DNA Replication Cell Division	Mitotic Cell Cycle Mitotic Nuclear Division Negative Regulation Of DNA Replication Response To Toxic Substance Viral Process Negative Regulation Of Chromatin Binding Negative Regulation Of Sister Chromatid Cohesion Positive Regulation Of Fibroblast Proliferation Cell Division Regulation Of Chromosome Condensation Protein Localization To Chromatin Regulation Of Cohesin Localization To Chromatin
Pathways		Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Mitotic Anaphase S Phase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Mitotic Anaphase S Phase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Periodontal microbiota ( 22699663)
Protein-Protein Interactions		3 interactors: CSNK2B UBC WAPAL	4 interactors: ARAP1 PDS5A RAD21 XRN1
Entrez ID		23244	23063
HPRD ID		11537	11072
Ensembl ID		ENSG00000121892	ENSG00000062650
Uniprot IDs		G1UI16 Q29RF7	Q7Z5K2
PDB IDs			4K6J
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Cell Cycle Negative Regulation Of Sister Chromatid Cohesion Regulation Of Chromosome Condensation Regulation Of Binding Regulation Of Cohesin Localization To Chromatin Negative Regulation Of Chromatin Binding Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Cytokine-mediated Signaling Pathway Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Process Endothelial Tube Morphogenesis Viral Protein Processing Protein Localization To Chromatin Viral Process Cellular Response To Cytokine Stimulus Regulation Of Sister Chromatid Cohesion Negative Regulation Of Blood Vessel Endothelial Cell Migration Mitotic Cell Cycle Process Response To Cytokine Positive Regulation Of Protein Phosphorylation Regulation Of Activin Receptor Signaling Pathway Notch Receptor Processing Regulation Of Protein Kinase Activity Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Kinase Activity Glycogen Biosynthetic Process Intracellular Transport Of Virus Protein Localization To Chromosome Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Negative Regulation Of Endothelial Cell Migration Regulation Of Cell Cycle Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Chromosome Segregation Polysaccharide Biosynthetic Process Cell Cycle Process Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Type I Interferon Production Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Phosphorylation Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of DNA Replication Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Cellular Protein Metabolic Process	Actin Filament Reorganization Involved In Cell Cycle Cell Cycle Process Chromosome Segregation Actin Filament Reorganization Cell Cycle Mitotic Nuclear Division Nuclear MRNA Surveillance RNA Surveillance Histone MRNA Catabolic Process Negative Regulation Of Stress Fiber Assembly Cell Division RRNA Catabolic Process Protein Localization To Chromatin Negative Regulation Of Actin Filament Bundle Assembly Mitotic Sister Chromatid Cohesion Positive Regulation Of Receptor Recycling Positive Regulation Of Cdc42 GTPase Activity Histone MRNA Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Receptor Recycling Regulation Of Cdc42 GTPase Activity Mitotic Cell Cycle Process Protein Localization To Chromosome Sister Chromatid Cohesion Regulation Of Cdc42 Protein Signal Transduction Mitotic Cell Cycle Positive Regulation Of Filopodium Assembly Reciprocal Meiotic Recombination Negative Regulation Of DNA Replication Regulation Of Filopodium Assembly Organelle Organization Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Stress Fiber Assembly Actin Cytoskeleton Reorganization Regulation Of ARF GTPase Activity Mitotic Sister Chromatid Segregation
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