WAPAL

Gene Name		wings apart-like homolog (Drosophila)
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Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Cohesin Complex Microtubule Cytoskeleton Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding
	Biological Process	Mitotic Cell Cycle Mitotic Nuclear Division Negative Regulation Of DNA Replication Response To Toxic Substance Viral Process Negative Regulation Of Chromatin Binding Negative Regulation Of Sister Chromatid Cohesion Positive Regulation Of Fibroblast Proliferation Cell Division Regulation Of Chromosome Condensation Protein Localization To Chromatin Regulation Of Cohesin Localization To Chromatin
Pathways		Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Mitotic Anaphase S Phase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Periodontal microbiota ( 22699663)
Protein-protein Interactions		4 interactors: ARAP1 PDS5A RAD21 XRN1
Entrez ID		23063
HPRD ID		11072
Ensembl ID		ENSG00000062650
Uniprot IDs		Q7Z5K2
PDB IDs		4K6J
Enriched GO Terms of Interacting Partners?		Actin Filament Reorganization Involved In Cell Cycle Cell Cycle Process Chromosome Segregation Actin Filament Reorganization Cell Cycle Mitotic Nuclear Division Nuclear MRNA Surveillance RNA Surveillance Histone MRNA Catabolic Process Negative Regulation Of Stress Fiber Assembly Cell Division RRNA Catabolic Process Protein Localization To Chromatin Negative Regulation Of Actin Filament Bundle Assembly Mitotic Sister Chromatid Cohesion Positive Regulation Of Receptor Recycling Positive Regulation Of Cdc42 GTPase Activity Histone MRNA Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Receptor Recycling Regulation Of Cdc42 GTPase Activity Mitotic Cell Cycle Process Protein Localization To Chromosome Sister Chromatid Cohesion Regulation Of Cdc42 Protein Signal Transduction Mitotic Cell Cycle Positive Regulation Of Filopodium Assembly Reciprocal Meiotic Recombination Negative Regulation Of DNA Replication Regulation Of Filopodium Assembly Organelle Organization Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Stress Fiber Assembly Actin Cytoskeleton Reorganization Regulation Of ARF GTPase Activity Mitotic Sister Chromatid Segregation
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