WAPAL and PDS5A

Number of citations of the paper that reports this interaction (PMID 21111234)
42

Data Source:
BioGRID (pull down)

		WAPAL	PDS5A
Gene Name		wings apart-like homolog (Drosophila)	PDS5 cohesin associated factor A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Cohesin Complex Microtubule Cytoskeleton Intracellular Membrane-bounded Organelle	Chromosome, Centromeric Region Chromatin Nucleoplasm Chromosome Cytosol Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Mitotic Nuclear Division Negative Regulation Of DNA Replication Response To Toxic Substance Viral Process Negative Regulation Of Chromatin Binding Negative Regulation Of Sister Chromatid Cohesion Positive Regulation Of Fibroblast Proliferation Cell Division Regulation Of Chromosome Condensation Protein Localization To Chromatin Regulation Of Cohesin Localization To Chromatin	Mitotic Cell Cycle Mitotic Sister Chromatid Cohesion Negative Regulation Of DNA Replication Cell Division
Pathways		Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Mitotic Anaphase S Phase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Mitotic Anaphase S Phase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Periodontal microbiota ( 22699663)
Protein-Protein Interactions		4 interactors: ARAP1 PDS5A RAD21 XRN1	3 interactors: CSNK2B UBC WAPAL
Entrez ID		23063	23244
HPRD ID		11072	11537
Ensembl ID		ENSG00000062650	ENSG00000121892
Uniprot IDs		Q7Z5K2	G1UI16 Q29RF7
PDB IDs		4K6J
Enriched GO Terms of Interacting Partners?		Actin Filament Reorganization Involved In Cell Cycle Cell Cycle Process Chromosome Segregation Actin Filament Reorganization Cell Cycle Mitotic Nuclear Division Nuclear MRNA Surveillance RNA Surveillance Histone MRNA Catabolic Process Negative Regulation Of Stress Fiber Assembly Cell Division RRNA Catabolic Process Protein Localization To Chromatin Negative Regulation Of Actin Filament Bundle Assembly Mitotic Sister Chromatid Cohesion Positive Regulation Of Receptor Recycling Positive Regulation Of Cdc42 GTPase Activity Histone MRNA Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Receptor Recycling Regulation Of Cdc42 GTPase Activity Mitotic Cell Cycle Process Protein Localization To Chromosome Sister Chromatid Cohesion Regulation Of Cdc42 Protein Signal Transduction Mitotic Cell Cycle Positive Regulation Of Filopodium Assembly Reciprocal Meiotic Recombination Negative Regulation Of DNA Replication Regulation Of Filopodium Assembly Organelle Organization Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Stress Fiber Assembly Actin Cytoskeleton Reorganization Regulation Of ARF GTPase Activity Mitotic Sister Chromatid Segregation	Mitotic Cell Cycle Cell Cycle Negative Regulation Of Sister Chromatid Cohesion Regulation Of Chromosome Condensation Regulation Of Binding Regulation Of Cohesin Localization To Chromatin Negative Regulation Of Chromatin Binding Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Cytokine-mediated Signaling Pathway Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Process Endothelial Tube Morphogenesis Viral Protein Processing Protein Localization To Chromatin Viral Process Cellular Response To Cytokine Stimulus Regulation Of Sister Chromatid Cohesion Negative Regulation Of Blood Vessel Endothelial Cell Migration Mitotic Cell Cycle Process Response To Cytokine Positive Regulation Of Protein Phosphorylation Regulation Of Activin Receptor Signaling Pathway Notch Receptor Processing Regulation Of Protein Kinase Activity Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Kinase Activity Glycogen Biosynthetic Process Intracellular Transport Of Virus Protein Localization To Chromosome Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Negative Regulation Of Endothelial Cell Migration Regulation Of Cell Cycle Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Chromosome Segregation Polysaccharide Biosynthetic Process Cell Cycle Process Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Type I Interferon Production Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Phosphorylation Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of DNA Replication Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Cellular Protein Metabolic Process
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