ASB2

Gene Name		ankyrin repeat and SOCS box containing 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cul5-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Protein Polyubiquitination Signal Transduction Intracellular Signal Transduction Skeletal Muscle Cell Differentiation Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Myoblast Differentiation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: FLNA FLNB RNF7 SMAD9 TCEB2 UBC UBE2D1
Entrez ID		51676
HPRD ID		05768
Ensembl ID		ENSG00000100628
Uniprot IDs		Q96Q27
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Response To Hypoxia Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Transforming Growth Factor Beta Receptor Signaling Pathway Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transcription From RNA Polymerase II Promoter Response To Stress Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Cellular Response To Stimulus Response To Abiotic Stimulus TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Transcription, DNA-templated MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway RNA Biosynthetic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity BMP Signaling Pathway Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Ubiquitination Toll-like Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Cellular Response To Stress Negative Regulation Of Protein Catabolic Process Response To Growth Factor Response To Stimulus Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Cell Surface Receptor Signaling Pathway Signal Transduction Mitotic Cell Cycle Process RNA Metabolic Process Activation Of Innate Immune Response
Tagcloud ?		ablating accelerating ankyrin associate associates box bridges cul cul1 cul5 cullin demanding dimeric dn e2a e3 elonginb exerts monomeric notch partly shifting sirnas skp1 skp2 socs transcriptionally turnover versatile