ASB2

Description		ankyrin repeat and SOCS box containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Stress Fiber Nucleus Cytoplasm Cytosol Cytoskeleton Z Disc
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity Cullin Family Protein Binding
	Biological Process	Heart Looping Ubiquitin-dependent Protein Catabolic Process Signal Transduction Skeletal Muscle Atrophy Protein Ubiquitination Actin Cytoskeleton Organization Intracellular Signal Transduction Skeletal Muscle Cell Differentiation Dendritic Cell Migration Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cardiac Muscle Cell Differentiation Cardiac Muscle Cell Development Podosome Assembly Regulation Of Barbed-end Actin Filament Capping
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Neutrophil percentage of granulocytes ( 27863252) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Sum eosinophil basophil counts ( 27863252)
Novel Interacting Genes		1 novel interacting genes: TRIP11
Interacting Genes		6 interacting genes: ELOB FLNA FLNB SMAD9 UBC UBE2D1
Entrez ID		51676
HPRD ID		05768
Ensembl ID		ENSG00000100628
Uniprot IDs		Q96Q27
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Modification Process Glycoprotein Ib-IX-V Complex Cell Cortex Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Actin Filament Binding Protein Localization To Bicellular Tight Junction Epithelial Cell Development Cytoplasm Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Fc-gamma Receptor I Complex Binding Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Formation Of Radial Glial Scaffolds Tubulin Deacetylation Cell Morphogenesis Z Disc Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Myb Complex Protein Metabolic Process Establishment Of Sertoli Cell Barrier SMAD Protein Complex Target-directed MiRNA Degradation Protein Modification By Small Protein Conjugation Elongin Complex VCB Complex Protein Ubiquitination Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Vesicle Tethering To Golgi
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