CLIP4 and MAP7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLIP4	MAP7
Description		CAP-Gly domain containing linker protein family member 4	microtubule associated protein 7
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GO Annotations	Cellular Component	Nucleus Cell Cortex Microtubule Plus-end	Cytoplasm Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Plasma Membrane Microtubule Cytoskeleton Membrane Basolateral Plasma Membrane Axon Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Microtubule Plus-end Binding	Signaling Receptor Binding Structural Molecule Activity Protein Binding
	Biological Process	Cytoplasmic Microtubule Organization	Microtubule Cytoskeleton Organization Response To Osmotic Stress Establishment Or Maintenance Of Cell Polarity Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Cerebrospinal fluid sTREM-2 levels ( 31708768) Lung cancer ( 34062886) Pursuit maintenance gain ( 29064472)
Interacting Genes		37 interacting genes: APP CDK5RAP2 CLIP1 CMYA5 DCAF6 DES DST DYNC2LI1 GLP1R HSF2BP JAKMIP2 KIF1B KIFC3 LZTS2 MAGEA12 MAP7 MAP7D1 MEOX2 MYBPC1 MYH3 PDE4DIP PEG10 RPS13 RPS27L RUNX1 SIX2 SON TACC3 TAF1 TNNT1 TNNT3 TPM1 TRIM32 TRIP13 TTN TULP3 ZNF114	9 interacting genes: CCDC70 CLIP4 CLK1 POT1 SRPK2 TERF1 TRPV4 UBC ZNF114
Entrez ID		79745	9053
HPRD ID		08634	04982
Ensembl ID		ENSG00000115295	ENSG00000135525
Uniprot IDs		A0A8I5KXU9 A0A8I5QKP4 A0A8I5QKV0 A8K6D0 B7Z936 G3XAK3 Q8N3C7	A0A087WZ40 B7Z3E1 B7Z3Y3 B7ZB64 Q14244
PDB IDs		2Z0W	7SGS
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Sarcomere Organization Organelle Organization Microtubule-based Process Microtubule Cytoskeleton Organization Actomyosin Structure Organization Microtubule Skeletal Muscle Contraction Striated Muscle Contraction Microtubule Binding Muscle Filament Sliding Muscle Contraction Actin-myosin Filament Sliding Centrosome Actin Cytoskeleton Organization Cytoskeleton Microtubule Plus-end Microtubule Cytoskeleton Muscle System Process M Band Actin Filament-based Process Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Microtubule Polymerization Actin-mediated Cell Contraction Female Meiosis I Structural Constituent Of Muscle Troponin Complex Myofibril Male Meiotic Nuclear Division Regulation Of Supramolecular Fiber Organization Actin Filament-based Movement Contractile Muscle Fiber Tropomyosin Binding Regulation Of Microtubule Polymerization Cytoskeletal Protein Binding Regulation Of Microtubule Cytoskeleton Organization Transport Along Microtubule Meiotic Nuclear Division Female Meiotic Nuclear Division Axo-dendritic Transport Positive Regulation Of Cytoskeleton Organization Supramolecular Fiber Organization Retrograde Axonal Transport Microtubule Plus-end Binding Positive Regulation Of Protein Polymerization Cytoskeleton-dependent Intracellular Transport Myosin Filament Nuclear Division Regulation Of Cytoskeleton Organization Amyloid-beta Complex	Shelterin Complex Nuclear Telomere Cap Complex Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Osmosensor Activity Blood Vessel Endothelial Cell Delamination Stretch-activated, Monoatomic Cation-selective, Calcium Channel Activity Cytoplasmic Microtubule Organization Positive Regulation Of Telomere Maintenance DNA Biosynthetic Process Negative Regulation Of Chromosome Organization Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of DNA Biosynthetic Process Positive Regulation Of Telomeric Loop Disassembly Positive Regulation Of Macrophage Inflammatory Protein 1 Alpha Production Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Cellular Hypotonic Salinity Response Vasopressin Secretion Mannose-ethanolamine Phosphotransferase Activity Nuclear Speck Organization Telomeric D-loop Binding Telomere Assembly Telomere Organization Negative Regulation Of DNA Metabolic Process Positive Regulation Of Organelle Organization Single-stranded Telomeric DNA Binding
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