ERP44 and CYLC2

		ERP44	CYLC2
Description		endoplasmic reticulum protein 44	cylicin 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cell Surface Specific Granule Lumen Extracellular Exosome	Nucleus Cytoplasm Cytoskeleton Perinuclear Theca Cytoskeletal Calyx
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding	Structural Constituent Of Cytoskeleton
	Biological Process	Protein Folding Response To Unfolded Protein Glycoprotein Metabolic Process Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis	Cytoskeleton Organization Spermatogenesis Cell Differentiation
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Preeclampsia ( 23551011)	Chronic rhinosinusitis ( 33393196) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		3 interacting genes: ERO1A ERO1B ITPR1	13 interacting genes: AURKA BUB1 CDKN2A EGFR ERBB2 MAP2K4 MCC MLH1 MLH3 MUTYH NRAS SMAD2 STK11
Entrez ID		23071	1539
HPRD ID		10290	04945
Ensembl ID		ENSG00000023318	ENSG00000155833
Uniprot IDs		A0A384MEE7 Q9BS26	Q14093 Q6PEJ5
PDB IDs		2R2J 5GU6 5GU7 5HQP 5XWM
Enriched GO Terms of Interacting Partners?		Calcineurin Complex Thiol Oxidase Activity Protein Folding In Endoplasmic Reticulum Protein-disulfide Reductase Activity Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis FAD Binding Endoplasmic Reticulum Membrane Sphingolipid Floppase Activity Release Of Sequestered Calcium Ion Into Cytosol Inositol 1,4,5-trisphosphate Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Levels Negative Regulation Of Sequestering Of Calcium Ion Response To Vitamin B3 Positive Regulation Of High-density Lipoprotein Particle Assembly Apolipoprotein A-I Receptor Activity Cytoskeletal Calyx Endoplasmic Reticulum-Golgi Intermediate Compartment Organization	Regulation Of Epithelial Cell Proliferation Chiasma Protein Kinase Activity Intracellular Signal Transduction Mismatch Repair ATP Binding Kinase Activity Negative Regulation Of Immature T Cell Proliferation In Thymus Mismatch Repair Complex Negative Regulation Of Immature T Cell Proliferation MutSalpha Complex Binding Nucleotide Binding ERBB2-EGFR Signaling Pathway Negative Regulation Of T Cell Differentiation In Thymus Intracellular Signaling Cassette Mismatched DNA Binding Regulation Of Immature T Cell Proliferation In Thymus ATP-dependent DNA Damage Sensor Activity Cellular Response To Stress Apoptotic Signaling Pathway Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Mitotic Cell Cycle Phase Transition Protein Serine Kinase Activity Nucleoplasm Disordered Domain Specific Binding Response To Stress Negative Regulation Of Multicellular Organismal Process Regulation Of T Cell Differentiation In Thymus Cell Population Proliferation Positive Regulation Of Protein Modification Process ERBB2 Signaling Pathway Protein Tyrosine Kinase Activity Synaptonemal Complex Negative Regulation Of Epithelial Cell Proliferation Regulation Of Protein Phosphorylation Reciprocal Meiotic Recombination Protein Serine/threonine Kinase Activity Regulation Of Cell Growth Nucleus Regulation Of Phosphorylation Signal Transduction Positive Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Cycle Phase Transition Condensed Chromosome Epithelial Cell Proliferation Homologous Recombination Chromatin Binding Apoptotic Process Positive Regulation Of Epithelial Cell Proliferation
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