ERP44 and ERO1A

Number of citations of the paper that reports this interaction (PubMedID 11847130)
46

Data Source:
HPRD (in vivo)

		ERP44	ERO1A
Description		endoplasmic reticulum protein 44	endoplasmic reticulum oxidoreductase 1 alpha
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GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cell Surface Specific Granule Lumen Extracellular Exosome	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Lumen Membrane Dendrite Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding	Protein Binding Protein-disulfide Reductase Activity Oxidoreductase Activity Thiol Oxidase Activity FAD Binding
	Biological Process	Protein Folding Response To Unfolded Protein Glycoprotein Metabolic Process Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis	Protein Folding Apoptotic Process Response To Oxidative Stress Transforming Growth Factor Beta Receptor Signaling Pathway Skeletal Muscle Tissue Development Response To Temperature Stimulus L-ascorbic Acid Metabolic Process Extracellular Matrix Organization Collagen Fibril Organization Endoplasmic Reticulum Unfolded Protein Response Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Protein Modification Process Cell Redox Homeostasis Brown Fat Cell Differentiation Release Of Sequestered Calcium Ion Into Cytosol Protein Maturation Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia
Pathways		Neutrophil degranulation	Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Preeclampsia ( 23551011)	Heel bone mineral density ( 30598549) Urine 6-bromotryptophan levels in chronic kidney disease ( 32572055)
Interacting Genes		3 interacting genes: ERO1A ERO1B ITPR1	14 interacting genes: APPBP2 EBF1 ERP44 GPX7 GPX8 GRSF1 LHX4 LINC01554 OGT P4HB PDIA3 PDILT PELI2 RHOU
Entrez ID		23071	30001
HPRD ID		10290	13278
Ensembl ID		ENSG00000023318	ENSG00000197930
Uniprot IDs		A0A384MEE7 Q9BS26	Q96HE7
PDB IDs		2R2J 5GU6 5GU7 5HQP 5XWM	3AHQ 3AHR
Enriched GO Terms of Interacting Partners?		Calcineurin Complex Thiol Oxidase Activity Protein Folding In Endoplasmic Reticulum Protein-disulfide Reductase Activity Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis FAD Binding Endoplasmic Reticulum Membrane Sphingolipid Floppase Activity Release Of Sequestered Calcium Ion Into Cytosol Inositol 1,4,5-trisphosphate Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Levels Negative Regulation Of Sequestering Of Calcium Ion Response To Vitamin B3 Positive Regulation Of High-density Lipoprotein Particle Assembly Apolipoprotein A-I Receptor Activity Cytoskeletal Calyx Endoplasmic Reticulum-Golgi Intermediate Compartment Organization	Protein Disulfide Isomerase Activity Endoplasmic Reticulum Lumen Protein Folding Protein Folding In Endoplasmic Reticulum Cellular Response To Interleukin-7 Response To Interleukin-7 Cul2-RING Ubiquitin Ligase Complex Glutathione Peroxidase Activity Protein-disulfide Reductase Activity Peroxidase Activity Isomerase Activity Transport Of Viral Material Towards Nucleus Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Response To Endoplasmic Reticulum Stress
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