POMZP3 and NMI

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		POMZP3	NMI
Description		POM121 and ZP3 fusion	N-myc and STAT interactor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nuclear Membrane	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function		Protein Binding Identical Protein Binding
	Biological Process		Macrophage Activation Involved In Immune Response Immune System Process Cell Surface Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Toll-like Receptor 4 Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Positive Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Protein K48-linked Ubiquitination Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Protein K48-linked Ubiquitination
Pathways			SARS-CoV-1 activates/modulates innate immune responses
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: ADORA2A APP BARD1 NMI	57 interacting genes: ANKRD13C-DT BRAT1 BRCA1 BRMS1 C1orf216 CDKN2A CDKN2D CNKSR3 CNOT7 COPS7B CYP2E1 EMILIN1 EXOSC5 GCSH GOLGA8EP HDDC3 HGS HOXC9 HSPA8 HSPH1 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MCPH1 MORF4L1 MTMR6 MTMR9 MYC MYCN MYOM3 NECAP2 POMZP3 PSMA1 RYBP SCEL SFR1 SH3GLB2 SINHCAF SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 THAP8 TRAF5 TRIM72 TRIP12 TUBA3C TUBA3E TXLNA TXLNB UBE2I
Entrez ID		22932	9111
HPRD ID		15974	04632
Ensembl ID		ENSG00000146707	ENSG00000123609
Uniprot IDs		Q6PJE2	Q13287
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Long-term Synaptic Potentiation Astrocyte Activation Regulation Of Long-term Synaptic Potentiation Regulation Of Inflammatory Response Regulation Of Protein Transport Macrophage Activation Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Programmed Cell Death Regulation Of Establishment Of Protein Localization Cell Activation Positive Regulation Of Apoptotic Process Regulation Of Intracellular Signal Transduction Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of MRNA 3'-end Processing Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Defense Response Response To Purine-containing Compound Positive Regulation Of Synaptic Transmission Central Nervous System Development Acetylcholine Receptor Activator Activity Positive Regulation Of Protein Metabolic Process Lipoprotein Particle Myeloid Leukocyte Activation Positive Regulation Of Protein Import Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Protein Localization Positive Regulation Of Acetylcholine Secretion, Neurotransmission PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Inflammatory Response Cell Activation Involved In Immune Response Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein K48-linked Ubiquitination Locomotory Behavior	Nucleoplasm Cell Surface Receptor Signaling Pathway Via JAK-STAT Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cell Surface Receptor Signaling Pathway Via STAT Growth Hormone Receptor Signaling Pathway Interleukin-9-mediated Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Cell Population Proliferation RNA Polymerase II Transcription Regulator Complex Negative Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleic Acid Metabolic Process Regulation Of Programmed Cell Death Regulation Of Erythrocyte Differentiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cell Population Proliferation Development Of Secondary Female Sexual Characteristics Development Of Secondary Male Sexual Characteristics DNA-binding Transcription Factor Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sin3-type Complex Regulation Of Apoptotic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Differentiation DNA-templated Transcription Positive Regulation Of Mesenchymal Cell Proliferation Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Negative Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Development Of Secondary Sexual Characteristics Positive Regulation Of Gene Expression Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Metabolic Process
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