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AGXT2
Gene Name
alanine--glyoxylate aminotransferase 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mitochondrion
Mitochondrial Matrix
Molecular Function
Alanine-glyoxylate Transaminase Activity
Beta-alanine-pyruvate Transaminase Activity
Pyridoxal Phosphate Binding
(R)-3-amino-2-methylpropionate-pyruvate Transaminase Activity
Biological Process
Pyrimidine Nucleobase Metabolic Process
Glyoxylate Catabolic Process
Glycine Biosynthetic Process, By Transamination Of Glyoxylate
L-alanine Catabolic Process, By Transamination
Cellular Nitrogen Compound Metabolic Process
Small Molecule Metabolic Process
Positive Regulation Of Nitric Oxide Biosynthetic Process
Pyrimidine Nucleoside Catabolic Process
Glyoxylate Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Pathways
Pyrimidine catabolism
Glyoxylate metabolism
Pyrimidine metabolism
Metabolism of nucleotides
Metabolism of amino acids and derivatives
Drugs
Pyridoxal Phosphate
Pyruvic acid
Glycine
L-Alanine
Diseases
GWAS
Metabolite levels (
21931564
)
Urinary metabolites (
21572414
)
Protein-protein Interactions
2 interactors:
ALDOB
CYP2E1
Entrez ID
64902
HPRD ID
10638
Ensembl ID
ENSG00000113492
Uniprot IDs
E9PDL7
Q9BYV1
PDB IDs
Enriched GO Terms of Interacting Partners
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Fructose Catabolic Process
Fructose 1,6-bisphosphate Metabolic Process
Monoterpenoid Metabolic Process
Vacuolar Proton-transporting V-type ATPase Complex Assembly
NADH Oxidation
Response To Ozone
Monocarboxylic Acid Metabolic Process
NADH Metabolic Process
Epoxygenase P450 Pathway
Fructose Metabolic Process
Exogenous Drug Catabolic Process
Drug Catabolic Process
Carboxylic Acid Metabolic Process
Organic Acid Metabolic Process
Positive Regulation Of ATPase Activity
Drug Metabolic Process
Regulation Of ATPase Activity
Oxidation-reduction Process
NAD Metabolic Process
Gluconeogenesis
Arachidonic Acid Metabolic Process
Hexose Biosynthetic Process
Catabolic Process
Nicotinamide Nucleotide Metabolic Process
Triglyceride Metabolic Process
Glycolytic Process
Icosanoid Metabolic Process
Unsaturated Fatty Acid Metabolic Process
Neutral Lipid Metabolic Process
Small Molecule Metabolic Process
Long-chain Fatty Acid Metabolic Process
Isoprenoid Metabolic Process
Pyruvate Metabolic Process
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Response To Ethanol
Glucose Metabolic Process
Response To Xenobiotic Stimulus
Carbohydrate Catabolic Process
Carbohydrate Biosynthetic Process
Response To Reactive Oxygen Species
Pathogenesis
Hexose Metabolic Process
Monosaccharide Metabolic Process
Steroid Metabolic Process
Fatty Acid Metabolic Process
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