ZNF365 and NDE1

Number of citations of the paper that reports this interaction (PMID 16682949)
12

Data Source:
HPRD (in vivo, two hybrid)

		ZNF365	NDE1
Gene Name		zinc finger protein 365	nudE neurodevelopment protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center	Kinetochore Condensed Chromosome Kinetochore Centrosome Cytosol Kinesin Complex Microtubule Membrane Spindle Pole Centrosome Cleavage Furrow
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process		G2/M Transition Of Mitotic Cell Cycle Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Neuron Migration Organelle Organization Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Neuroblast Proliferation Cell Migration Cerebral Cortex Development Vesicle Transport Along Microtubule Centrosome Duplication Cell Division Establishment Of Chromosome Localization Centrosome Localization
Pathways			Mitotic Prometaphase Organelle biogenesis and maintenance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS		Atopic dermatitis ( 23042114) Breast cancer ( 21908515 23535729 23535733 20453838) Breast size ( 22747683) Crohn's disease ( 18587394 22936669 22412388 21102463) Ewing sarcoma ( 22327514) Intelligence ( 22449649) Mammographic density ( 21278746)
Protein-Protein Interactions		3 interactors: APP DISC1 NDE1	27 interactors: AR ARNT2 BZRAP1 CDK1 DISC1 FAM9B GOLGA2 HOXA2 LZTS2 MAPK1 MED4 MKRN3 NDC80 NDEL1 PAFAH1B1 REL TFIP11 TRIM27 TTC1 TUBG1 UBQLN1 USHBP1 WAC YWHAG YWHAQ ZNF365 ZNF398
Entrez ID		22891	54820
HPRD ID		06380	14815
Ensembl ID		ENSG00000138311	ENSG00000072864
Uniprot IDs		Q70YC4 Q70YC5	Q9NXR1
PDB IDs
Enriched GO Terms of Interacting Partners?		Forebrain Development Brain Development Microtubule-based Process Head Development Regulation Of Synapse Structure Or Activity Neural Precursor Cell Proliferation Central Nervous System Development Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cerebral Cortex Development Neuron Migration Locomotion Pallium Development Synaptic Growth At Neuromuscular Junction Movement Of Cell Or Subcellular Component Generation Of Neurons Collateral Sprouting In Absence Of Injury Neurogenesis Telencephalon Development Cellular Calcium Ion Homeostasis Positive Regulation Of Proteolysis Calcium Ion Homeostasis Microtubule-based Movement Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Cellular Metal Ion Homeostasis Nervous System Development Cellular Cation Homeostasis Microtubule Cytoskeleton Organization Cellular Ion Homeostasis Cellular Localization Neuron Remodeling Metal Ion Homeostasis Cellular Chemical Homeostasis Regulation Of Neuron Differentiation Mitotic Centrosome Separation Ion Homeostasis Centrosome Separation Organ Development Mitochondrial Calcium Ion Homeostasis Cellular Copper Ion Homeostasis Regulation Of Proteolysis Regulation Of Synapse Maturation Microtubule Nucleation Cellular Homeostasis Regulation Of Neurogenesis TOR Signaling Cell Proliferation	Microtubule Cytoskeleton Organization Cell Cycle Mitotic Cell Cycle Mitotic Cell Cycle Process Cell Cycle Process G2/M Transition Of Mitotic Cell Cycle Microtubule-based Process Nuclear Envelope Disassembly Cellular Localization Positive Regulation Of Macromolecule Biosynthetic Process Cytoskeleton Organization Establishment Of Mitotic Spindle Orientation Positive Regulation Of Gene Expression Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Mitotic Nuclear Division Positive Regulation Of Cellular Biosynthetic Process Retrograde Axon Cargo Transport Spindle Localization Positive Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Cerebral Cortex Radially Oriented Cell Migration Nuclear Envelope Organization Regulation Of Cellular Localization Regulation Of Neurogenesis Organ Development Cell Proliferation Regulation Of Signaling Regulation Of Metabolic Process Establishment Of Localization In Cell Brain Development Cerebral Cortex Cell Migration Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Localization Head Development Mitotic Cell Cycle Phase Transition Telencephalon Cell Migration Cell Cycle Phase Transition Forebrain Cell Migration Regulation Of Cell Development Axonogenesis Positive Regulation Of Signal Transduction Regulation Of Neuron Differentiation Microtubule Organizing Center Organization Establishment Of Cell Polarity Positive Regulation Of Metabolic Process Microtubule Nucleation Axon Development Nervous System Development Nucleus Organization
Tagcloud ?		absolute ascertained automated dense esr1 estimates heritability heritable loci mammographic menopausal mlk1 nondense ntn4 percent rs10995190 rs17356907 rs2046210 rs6001930 rs9383938 rs9485372 sib sided swedish tab2 trait volume volumetric weaker	breaks catastrophic cohesin completing concurrent discovered disorders ensures evoked fate genomic heterochromatin impediment indispensible integrity layer mid neural neurological pool progenitor progenitors remodeler replication restrictive safeguarding stalled steps strand
Tagcloud (Difference) ?		absolute ascertained automated dense esr1 estimates heritability heritable loci mammographic menopausal mlk1 nondense ntn4 percent rs10995190 rs17356907 rs2046210 rs6001930 rs9383938 rs9485372 sib sided swedish tab2 trait volume volumetric weaker	breaks catastrophic cohesin completing concurrent discovered disorders ensures evoked fate genomic heterochromatin impediment indispensible integrity layer mid neural neurological pool progenitor progenitors remodeler replication restrictive safeguarding stalled steps strand
Tagcloud (Intersection) ?