ZNF572 and MLLT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF572	MLLT3
Description		zinc finger protein 572	MLLT3 super elongation complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Chromosome Cytosol Transcription Elongation Factor Complex Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	DNA Binding Chromatin Binding Protein Binding Histone Binding Molecular Adaptor Activity Modification-dependent Protein Binding Histone H3K18ac Reader Activity Histone H3K9ac Reader Activity Histone H3K27ac Reader Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process	Chromatin Organization Segment Specification Anterior/posterior Pattern Specification Gene Expression Positive Regulation Of DNA-templated Transcription Hematopoietic Stem Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Chromatin Organization Regulation Of Stem Cell Division Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways			Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Atrial fibrillation ( 29892015) Dietary fat liking ( 32516399) Estimated glomerular filtration rate ( 31152163) Glutathione peroxidase in non-alcoholic fatty liver disease x mastiha supplementation interaction ( 34025683) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Platelet distribution width ( 32888494) Response to montelukast in asthma (change in FEV1) ( 26083242) Systolic blood pressure ( 30578418)
Interacting Genes		60 interacting genes: ATOSB BEGAIN BOLA1 CADPS CARD9 CBY2 CCDC102B CCDC136 CCDC33 CDR2L CEP57L1 CEP70 CPNE7 DEUP1 DRC4 FSD2 GOLGA2 GPR50 HAP1 HOOK1 HOOK2 IL16 KATNBL1 KIF9 KIFC3 KLC3 KRT31 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 LZTS1 LZTS2 MDFI MEOX2 MLLT3 MTUS2 NDEL1 PRPH REL SPAG5 TFIP11 TRAF1 TRAF2 TRIM27 TRIM54 VIM WTAP YJU2B ZBTB1 ZBTB8A ZNF165 ZNF250 ZNF383 ZNF417 ZNF57 ZNF774 ZNF835	18 interacting genes: AFF1 ALKBH4 APP APPBP2 BCOR CBX8 CDK6 EEF1A1 H3C1 LRIF1 LRRK2 MCM6 NRIP1 PTN RBM48 SGK1 VAX1 ZNF572
Entrez ID		137209	4300
HPRD ID		15851	01163
Ensembl ID		ENSG00000180938	ENSG00000171843
Uniprot IDs		Q7Z3I7	A0A0S2Z448 P42568
PDB IDs			2LM0 2MV7 2N4Q 2NDF 2NDG 4TMP 5HJB 5HJD 5YYF 6B7G 6L5Z 6LS6 6MIL 6MIM 7EIC 7EID 7VKG 7VKH 8PJ7 8TLV 8TLW 8TLX 9ARO 9ARR
Enriched GO Terms of Interacting Partners?		Microtubule Binding Microtubule Intermediate Filament Keratin Filament Cytoskeleton Identical Protein Binding Microtubule-based Process Kinesin Complex Cytoskeleton-dependent Intracellular Transport Protein Binding Centrosome FHF Complex Microtubule Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Localization To Perinuclear Region Of Cytoplasm Microtubule-based Movement Ciliary Rootlet Thioesterase Binding Establishment Of Vesicle Localization Vesicle Transport Along Microtubule Cytoskeleton Organization Vesicle Localization	Cell Projection Morphogenesis Golgi-associated Vesicle Chromatin Organization Epigenetic Regulation Of Gene Expression Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Neuron Projection Morphogenesis Regulation Of Gene Expression Negative Regulation Of Long-term Synaptic Potentiation Response To Auditory Stimulus Cellular Response To Catecholamine Stimulus Regulation Of Metabolic Process Cellular Response To Manganese Ion Response To Catecholamine Response To Manganese Ion Nucleoplasm Regulation Of Neuroblast Proliferation Neuron Projection Arborization Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Neuroblast Proliferation Nuclear Retinoic Acid Receptor Binding Negative Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Memory Molecular Function Activator Activity Negative Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of RNA Metabolic Process Chromatin Remodeling Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Macromolecule Metabolic Process Dendrite Development Cyclin D2-CDK6 Complex Response To Polyamine Macromolecule Response To Reactive Oxygen Species Ovarian Follicle Rupture DNA N6-methyladenine Demethylase Activity Negative Regulation Of Tooth Mineralization BCOR Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?