ZNF572 and GPR50

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ZNF572	GPR50
Description		zinc finger protein 572	G protein-coupled receptor 50
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Plasma Membrane Postsynaptic Density Membrane Synapse
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	G Protein-coupled Receptor Activity Protein Binding Melatonin Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		60 interacting genes: ATOSB BEGAIN BOLA1 CADPS CARD9 CBY2 CCDC102B CCDC136 CCDC33 CDR2L CEP57L1 CEP70 CPNE7 DEUP1 DRC4 FSD2 GOLGA2 GPR50 HAP1 HOOK1 HOOK2 IL16 KATNBL1 KIF9 KIFC3 KLC3 KRT31 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 LZTS1 LZTS2 MDFI MEOX2 MLLT3 MTUS2 NDEL1 PRPH REL SPAG5 TFIP11 TRAF1 TRAF2 TRIM27 TRIM54 VIM WTAP YJU2B ZBTB1 ZBTB8A ZNF165 ZNF250 ZNF383 ZNF417 ZNF57 ZNF774 ZNF835	4 interacting genes: ARRB1 MTNR1A MTNR1B ZNF572
Entrez ID		137209	9248
HPRD ID		15851	02194
Ensembl ID		ENSG00000180938	ENSG00000102195
Uniprot IDs		Q7Z3I7	Q13585
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule Binding Microtubule Intermediate Filament Keratin Filament Cytoskeleton Identical Protein Binding Microtubule-based Process Kinesin Complex Cytoskeleton-dependent Intracellular Transport Protein Binding Centrosome FHF Complex Microtubule Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Localization To Perinuclear Region Of Cytoplasm Microtubule-based Movement Ciliary Rootlet Thioesterase Binding Establishment Of Vesicle Localization Vesicle Transport Along Microtubule Cytoskeleton Organization Vesicle Localization	Melatonin Receptor Activity G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Angiotensin Receptor Binding Negative Adaptation Of Signaling Pathway Desensitization Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Arrestin Family Protein Binding
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