FGF11 and NRDC

		FGF11	NRDC
Description		fibroblast growth factor 11	nardilysin convertase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Mitochondrion Mitochondrial Matrix Cytosol Cell Surface Dendrite Cell Projection
	Molecular Function	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity	Metalloendopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Metal Ion Binding Epidermal Growth Factor Binding Endopeptidase Activator Activity
	Biological Process	Signal Transduction Cell-cell Signaling Nervous System Development Neurogenesis	Proteolysis Positive Regulation Of Myelination Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Axonogenesis Positive Regulation Of Membrane Protein Ectodomain Proteolysis Negative Regulation Of Cold-induced Thermogenesis Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Pathways		Phase 0 - rapid depolarisation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278)	Appendicular lean mass ( 33097823)
Interacting Genes		4 interacting genes: HMBOX1 RPL22 STAC3 THAP1	6 interacting genes: CALCA H3C14 HBEGF NLGN3 PDYN POMC
Entrez ID		2256	4898
HPRD ID		03304	04036
Ensembl ID		ENSG00000161958	ENSG00000078618
Uniprot IDs		A0A7U3JVZ5 B7Z1C3 Q92914	G3V1R5 O43847 Q6UUU9
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Translation At Presynapse PML Body Telomere-telomerase Complex Assembly	Cell-cell Signaling Cell Communication Signaling Neuronal Dense Core Vesicle Hippocampal Mossy Fiber To CA3 Synapse Regulation Of System Process Regulation Of Glycogen Metabolic Process Positive Regulation Of Oxytocin Production Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Amylin Receptor 1 Signaling Pathway Calcitonin Receptor Binding Signaling Receptor Binding Endocytosis Amylin Receptor 2 Signaling Pathway Hormone Activity Insulin Receptor Complex Neuropeptide Signaling Pathway Opioid Receptor Binding Opioid Peptide Activity Cellular Pigmentation Type 1 Melanocortin Receptor Binding Positive Regulation Of Neutrophil Mediated Killing Of Fungus Type 4 Melanocortin Receptor Binding Positive Regulation Of Killing Of Cells Of Another Organism Type 3 Melanocortin Receptor Binding Response To Melanocyte-stimulating Hormone Asymmetric, Glutamatergic, Excitatory Synapse Rhythmic Synaptic Transmission Symmetric, GABA-ergic, Inhibitory Synapse
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