BRAT1 and MSGN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BRAT1	MSGN1
Description		BRCA1 associated ATM activator 1	mesogenin 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane	Chromatin Nucleus
	Molecular Function	Protein Binding Ribonuclease Inhibitor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Glucose Metabolic Process Apoptotic Process DNA Damage Response Cell Population Proliferation Response To Ionizing Radiation Cell Migration Positive Regulation Of Cell Growth Protein Localization To Nucleus Mitochondrion Localization Integrator Complex Assembly	Mesoderm Formation Somitogenesis Regulation Of Transcription By RNA Polymerase II Segment Specification Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Formation of paraxial mesoderm Somitogenesis
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Platelet distribution width ( 32888494)	Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699)
Interacting Genes		6 interacting genes: BRCA1 ENKD1 MSGN1 NMI USHBP1 WEE2-AS1	28 interacting genes: AP1B1 ATP11B BRAT1 CCDC172 CTAG1A CTAG1B DNALI1 EXOC7 FERD3L HAP1 ID1 ID2 ID3 IGFBP6 ITGB3BP LDOC1 MAGEA6 MYF5 MYL9 NECAB2 OST4 SERTAD3 TEPSIN TEX12 TRAF1 TTC23L ZMYND12 ZWINT
Entrez ID		221927	343930
HPRD ID		12914
Ensembl ID		ENSG00000106009	ENSG00000151379
Uniprot IDs		Q6PJG6	A6NI15
PDB IDs		4IFI 8R22 8R23 8R2D 8UIB
Enriched GO Terms of Interacting Partners?			Protein Dimerization Activity Transcription Regulator Inhibitor Activity Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Regulation Of Dopaminergic Neuron Differentiation Regulation Of DNA-binding Transcription Factor Activity
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