ZFY and KAT14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZFY	KAT14
Description		zinc finger protein Y-linked	lysine acetyltransferase 14
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Cytoplasm Mitotic Spindle ATAC Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	Histone Acetyltransferase Activity Protein Binding Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups LIM Domain Binding
	Biological Process	Ovarian Follicle Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Germ Cell Development Spermatogenesis Fertilization Post-embryonic Development Multicellular Organism Growth Positive Regulation Of Transcription By RNA Polymerase II Oocyte Development Homeostasis Of Number Of Cells Parental Behavior	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle
Pathways			HATs acetylate histones Formation of WDR5-containing histone-modifying complexes
Drugs		3-Cyclohexyl-L-alanine Picolinic acid
Diseases
GWAS			Thyroglobulin plasma levels ( 30929638)
Interacting Genes		4 interacting genes: DMRT3 KAT14 L3MBTL2 ZBTB9	11 interacting genes: ACTC1 CEP70 CSRP2 DPPA4 H3C1 H4C1 H4C16 MBIP TRIM27 TRIM54 ZFY
Entrez ID		7544	57325
HPRD ID		02466	16765
Ensembl ID		ENSG00000067646	ENSG00000149474
Uniprot IDs		P08048	A0A075B6H4 Q9H8E8
PDB IDs		1KLR 1KLS 1XRZ 5ZNF 7ZNF
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process LIM Domain Binding Male Sex Differentiation Ventral Spinal Cord Interneuron Specification Histone H4K20me1 Reader Activity Histone H4K20me2 Reader Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Odontogenesis Of Dentin-containing Tooth ATAC Complex Ectoderm Development Regulation Of Odontogenesis Regulation Of Macromolecule Biosynthetic Process Histone Acetyltransferase Activity Regulation Of Primary Metabolic Process Regulation Of Gene Expression Neuron Fate Specification Sex Differentiation Transmission Of Nerve Impulse Adult Walking Behavior Walking Behavior Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Metabolic Process Regulation Of Embryonic Development Nucleus Adult Locomotory Behavior Regulation Of Animal Organ Morphogenesis Cell Fate Specification RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Promoter-specific Chromatin Binding Stem Cell Proliferation	Nucleosome Telomere Organization Nucleosome Assembly Nucleosome Organization Structural Constituent Of Chromatin CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Protein-DNA Complex Assembly Protein Localization To Chromosome, Centromeric Region Regulation Of Megakaryocyte Differentiation Protein Localization To Chromatin Chromatin Remodeling Protein Heterodimerization Activity Chromosome Organization Chromatin Organization Negative Regulation Of Myeloid Cell Differentiation Protein Localization To Chromosome Actomyosin Structure Organization Organelle Organization Cytoplasmic Actin-based Contraction Involved In Cell Motility Mesenchyme Migration Z Disc
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