MEI4 and PHYHIPL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MEI4	PHYHIPL
Description		meiotic double-stranded break formation protein 4	phytanoyl-CoA 2-hydroxylase interacting protein like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lateral Element Chromosome	Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis Meiotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Brain volume in infants (white matter) ( 28763065) Cadmium levels ( 26025379) Daytime nap ( 33568662) HDL cholesterol levels in HIV infection ( 33109212) Macular thickness ( 30535121)	Daytime sleep phenotypes ( 27126917) Night sleep phenotypes ( 27126917)
Interacting Genes		36 interacting genes: AFMID AIRIM BAG4 C19orf25 CABP5 CDKN2D CHAF1A CPNE2 CST9L CTTNBP2 DNTT EIF5A FKBP6 GRB2 HSD3B7 IQGAP1 LGALS14 MACO1 METTL21A MLX MTMR9 MYO5B NGB NME7 OSGIN1 PAFAH1B3 PHYHIPL PLEKHA4 POLR1C R3HDM2 TRAPPC2L TRIM59 TSEN15 TSSK3 USHBP1 VPS26C	4 interacting genes: ERRFI1 HSPB1 MEI4 PDE9A
Entrez ID		101928601	84457
HPRD ID			15131
Ensembl ID		ENSG00000269964	ENSG00000165443
Uniprot IDs		A8MW99	Q96FC7
PDB IDs
Enriched GO Terms of Interacting Partners?			Regulation Of Interleukin-1 Production Negative Regulation Of Protein Kinase C Signaling Regulation Of Interleukin-1 Beta Production Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Intracellular Signal Transduction Uterine Epithelium Development Response To 1-oleoyl-sn-glycerol 3-phosphate Regulation Of Tumor Necrosis Factor Production Protein Kinase C Inhibitor Activity Negative Regulation Of Protein Autophosphorylation Oviduct Epithelium Development Cellular Response To Growth Factor Stimulus Regulation Of Protein Kinase C Signaling Negative Regulation Of Signal Transduction Positive Regulation Of Endothelial Cell Chemotaxis Regulation Of Protein Phosphorylation Protein Transport Along Microtubule Response To Growth Factor Negative Regulation Of Cell Communication Anterograde Axonal Protein Transport Contractile Muscle Fiber Negative Regulation Of Signaling Cyclic Nucleotide Catabolic Process CGMP Catabolic Process Regulation Of Muscle System Process Chondrocyte Proliferation Skin Morphogenesis Negative Regulation Of Signaling Receptor Activity Lung Vasculature Development Limb Joint Morphogenesis Fat Pad Development Progesterone Receptor Signaling Pathway Regulation Of Type B Pancreatic Cell Proliferation Lung Epithelium Development Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Protein Autophosphorylation Meiotic DNA Double-strand Break Formation Lateral Element Regulation Of Phosphorylation Negative Regulation Of Collagen Biosynthetic Process Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein Kinase Binding Cellular Hyperosmotic Response 3',5'-cyclic-AMP Phosphodiesterase Activity CGMP Metabolic Process Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Cardiac Muscle Hypertrophy In Response To Stress 3',5'-cyclic-GMP Phosphodiesterase Activity
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