SAXO4 and FKBP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SAXO4	FKBP6
Description		stabilizer of axonemal microtubules 4	FKBP prolyl isomerase family member 6 (inactive)
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cilium Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Synaptonemal Complex Fibrillar Center Nucleus Cytoplasm Cytosol Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	Protein Binding Phosphatase Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Identical Protein Binding Hsp90 Protein Binding
	Biological Process	Flagellated Sperm Motility	Protein Folding Spermatogenesis Cell Differentiation Regulatory NcRNA-mediated Gene Silencing PiRNA Processing Positive Regulation Of Viral Genome Replication Meiotic Cell Cycle Transposable Element Silencing By PiRNA-mediated DNA Methylation
Pathways			Meiotic synapsis PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS			Height ( 31562340) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		73 interacting genes: AKAP8L ALS2CL APP ATN1 ATPAF2 B9D2 BAG4 BCAS2 C10orf55 CATSPER1 CCDC57 CFTR COG6 COX5B CSTF2 CTDSP1 CYSRT1 DTX2 FAM168B FHL2 FHL3 FHL5 FKBP6 FRS3 GOLGA2 HGS HNRNPH1 HOMER3 HOXA1 HSF2BP INCA1 KCTD9 KPRP KRT31 KRTAP13-2 KRTAP19-5 KRTAP19-6 KRTAP3-1 KRTAP3-2 KRTAP6-2 KRTAP6-3 KRTAP8-1 LASP1 LMO2 LMO4 METTL27 MYO15B OIP5 OTUD7B PFDN5 PLA2G10 PLEKHG4 PLEKHN1 PPP1CA PPP1CC PRDM14 PRKAA2 QARS1 RBM11 RFX6 RIMBP3C SLAIN1 TEKT4 TFG TGM7 TRAF1 TRAF2 TRIB3 TSC1 UNKL VMAC WWOX ZMYND12	38 interacting genes: ACD ALDH3A1 CCDC198 CCNK CDK5RAP3 CFP CFTR CRACR2A DDIT4L DLGAP4 ECM1 EEF1D ENKD1 FAM107A GAPDH GSC2 HSP90AA1 IHO1 KANK2 KRT75 LZTS2 MAP3K1 MEI4 MEOX2 NME7 NTAQ1 PIAS2 PICK1 RAB11FIP2 RNF4 SAXO4 SUMO1P1 TEPSIN TINF2 TMEM9B TRIM55 TRIM63 ZNF655
Entrez ID		220004	8468
HPRD ID		16933	05326
Ensembl ID		ENSG00000162148	ENSG00000077800
Uniprot IDs		G3F4G3 Q7Z5V6	O75344
PDB IDs			3B7X
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding	Shelterin Complex Telomere Assembly Meiotic DNA Double-strand Break Formation Protein Binding Regulation Of Telomere Maintenance Via Telomerase Nuclear Telomere Cap Complex Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Localization To Chromosome, Telomeric Region
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