SAXO4 and ALS2CL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SAXO4	ALS2CL
Description		stabilizer of axonemal microtubules 4	ALS2 C-terminal like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cilium Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Cytoplasm Cytosol Cytoplasmic Vesicle
	Molecular Function	Protein Binding Phosphatase Binding	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Flagellated Sperm Motility	Endosomal Transport
Pathways			RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS
Interacting Genes		73 interacting genes: AKAP8L ALS2CL APP ATN1 ATPAF2 B9D2 BAG4 BCAS2 C10orf55 CATSPER1 CCDC57 CFTR COG6 COX5B CSTF2 CTDSP1 CYSRT1 DTX2 FAM168B FHL2 FHL3 FHL5 FKBP6 FRS3 GOLGA2 HGS HNRNPH1 HOMER3 HOXA1 HSF2BP INCA1 KCTD9 KPRP KRT31 KRTAP13-2 KRTAP19-5 KRTAP19-6 KRTAP3-1 KRTAP3-2 KRTAP6-2 KRTAP6-3 KRTAP8-1 LASP1 LMO2 LMO4 METTL27 MYO15B OIP5 OTUD7B PFDN5 PLA2G10 PLEKHG4 PLEKHN1 PPP1CA PPP1CC PRDM14 PRKAA2 QARS1 RBM11 RFX6 RIMBP3C SLAIN1 TEKT4 TFG TGM7 TRAF1 TRAF2 TRIB3 TSC1 UNKL VMAC WWOX ZMYND12	7 interacting genes: EEF1AKMT3 RAB22A RAB31 RAB5A RAB5C RSPH14 SAXO4
Entrez ID		220004	259173
HPRD ID		16933	10643
Ensembl ID		ENSG00000162148	ENSG00000178038
Uniprot IDs		G3F4G3 Q7Z5V6	Q60I27
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding	GDP Binding Early Endosome Endomembrane System GTPase Activity Phagocytic Vesicle Phagocytic Vesicle Membrane Plasma Membrane To Endosome Transport GTP Binding Endocytosis Regulation Of Vesicle Size Intracellular Protein Transport Import Into Cell Early Endosome Membrane Endosome Receptor Internalization Endocytic Vesicle G Protein Activity Protein Transport Endosome Organization Vesicle-mediated Transport Intracellular Transport Melanosome Ruffle Cell Projection Establishment Of Protein Localization Regulation Of Vesicle-mediated Transport Protein Localization To Early Endosome Early Phagosome Membrane Cytoplasmic Side Of Early Endosome Membrane Cellular Localization Late Endosome Establishment Of Localization In Cell Receptor-mediated Endocytosis Nucleotide Binding Amyloid-beta Clearance By Transcytosis Intracellular Protein Localization Motile Cilium Cytoplasmic Vesicle Regulation Of Cellular Component Size Regulation Of Endosome Size Endosomal Transport Phagosome Maturation Early Phagosome Radial Spoke Actin Cytoskeleton Endosome Membrane Protein Localization To Endosome Positive Regulation Of Phagocytosis, Engulfment Synaptic Vesicle Recycling Somatodendritic Compartment
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