CYB561A3 and GPR101

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYB561A3	GPR101
Description		cytochrome b561 family member A3	G protein-coupled receptor 101
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Lysosome Lysosomal Membrane Endosome Membrane Late Endosome Membrane	Plasma Membrane Membrane Receptor Complex
	Molecular Function	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Intracellular Iron Ion Homeostasis Transmembrane Transport	Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Body mass index ( 28892062)
Interacting Genes		23 interacting genes: AGPAT5 AOC1 AQP6 CD40 CD79A CLDN5 CLDN7 CREB3L3 EHHADH FFAR2 GPR101 GPR152 GPR37L1 GPX8 HERPUD2 KLRC1 LAPTM4B PVR RNF185 RNF5 SHISAL1 TM4SF18 TMEM31	20 interacting genes: AGPAT4 C1GALT1 CDIPT CYB561A3 DERL3 LAT NDUFB11 ORMDL3 RTP2 SLC35E4 SLC39A9 SLC41A1 SLC61A1 THSD7B TM4SF4 TMEM147 TMEM239 UNC93A UNC93B1 YIPF6
Entrez ID		220002	83550
HPRD ID		11316	02315
Ensembl ID		ENSG00000162144	ENSG00000165370
Uniprot IDs		F5H1Q2 Q8NBI2	Q96P66
PDB IDs			8W8Q 8W8R 8W8S
Enriched GO Terms of Interacting Partners?		Membrane Ubiquitin-like Protein Conjugating Enzyme Binding Positive Regulation Of Immune Response Positive Regulation Of Immune Effector Process Immune Response-regulating Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Apicolateral Plasma Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Positive Regulation Of Acute Inflammatory Response Positive Regulation Of Defense Response Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Protein Alpha-1,2-demannosylation Response To Endoplasmic Reticulum Stress Endoplasmic Reticulum Mannose Trimming Endoplasmic Reticulum Quality Control Compartment Protein Deglycosylation Bicellular Tight Junction Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Diamine Oxidase Activity Putrescine Oxidase Activity Histamine Oxidase Activity Nitrate Transmembrane Transporter Activity Regulation Of Immune Response Immune Response-activating Signaling Pathway Positive Regulation Of Natural Killer Cell Mediated Immunity Inhibitory MHC Class Ib Receptor Activity B Cell Proliferation G Protein-coupled Receptor Activity Plasma Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Positive Regulation Of Immune System Process Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Lymphocyte Mediated Immunity Activation Of Immune Response Bicellular Tight Junction Assembly Tight Junction Organization Tight Junction Assembly Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Innate Immune Response-activating Signaling Pathway Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Regulation Of Innate Immune Response Activation Of Innate Immune Response Regulation Of Acute Inflammatory Response HLA-E Specific Inhibitory MHC Class Ib Receptor Activity Receptor Complex Regulation Of T Cell Mediated Cytotoxicity	Membrane CDP-diacylglycerol Metabolic Process Intestinal Epithelial Cell Development Columnar/cuboidal Epithelial Cell Development
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