CYB561A3 and SHISAL1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		CYB561A3	SHISAL1
Name		cytochrome b561 family member A3	shisa like 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Lysosome Lysosomal Membrane Endosome Membrane Late Endosome Membrane	Membrane
	Molecular Function	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity	Protein Binding
	Biological Process	Intracellular Iron Ion Homeostasis Transmembrane Transport	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		23 interacting genes: AGPAT5 AOC1 AQP6 CD40 CD79A CLDN5 CLDN7 CREB3L3 EHHADH FFAR2 GPR101 GPR152 GPR37L1 GPX8 HERPUD2 KLRC1 LAPTM4B PVR RNF185 RNF5 SHISAL1 TM4SF18 TMEM31	28 interacting genes: ALG10 ALG10B ARLN ASPH CATSPERH CYB561A3 GIMAP5 GJB2 GPR151 GPR25 GYPC LPAR3 MFF MFSD6 PLPP6 PMP22 SCAMP5 SLC16A13 SLC35B2 SLC38A7 SLC39A7 SLC41A2 SLC52A1 SLC61A1 TMEM128 TMEM140 TMEM42 ZFPL1
Entrez ID		220002	85352
HPRD ID		11316	19361
Ensembl ID		ENSG00000162144	ENSG00000138944
Uniprot IDs		F5H1Q2 Q8NBI2	Q3SXP7
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Membrane Ubiquitin-like Protein Conjugating Enzyme Binding Positive Regulation Of Immune Response Positive Regulation Of Immune Effector Process Immune Response-regulating Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Apicolateral Plasma Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Positive Regulation Of Acute Inflammatory Response Positive Regulation Of Defense Response Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Protein Alpha-1,2-demannosylation Response To Endoplasmic Reticulum Stress Endoplasmic Reticulum Mannose Trimming Endoplasmic Reticulum Quality Control Compartment Protein Deglycosylation Bicellular Tight Junction Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Diamine Oxidase Activity Putrescine Oxidase Activity Histamine Oxidase Activity Nitrate Transmembrane Transporter Activity Regulation Of Immune Response Immune Response-activating Signaling Pathway Positive Regulation Of Natural Killer Cell Mediated Immunity Inhibitory MHC Class Ib Receptor Activity B Cell Proliferation G Protein-coupled Receptor Activity Plasma Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Positive Regulation Of Immune System Process Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Lymphocyte Mediated Immunity Activation Of Immune Response Bicellular Tight Junction Assembly Tight Junction Organization Tight Junction Assembly Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Innate Immune Response-activating Signaling Pathway Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Regulation Of Innate Immune Response Activation Of Innate Immune Response Regulation Of Acute Inflammatory Response HLA-E Specific Inhibitory MHC Class Ib Receptor Activity Receptor Complex Regulation Of T Cell Mediated Cytotoxicity	Membrane Dolichyl Pyrophosphate Glc2Man9GlcNAc2 Alpha-1,2-glucosyltransferase Activity Bleb Assembly Transmembrane Transport Dolichol-linked Oligosaccharide Biosynthetic Process