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ABCD1 and RPSA
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
ABCD1
RPSA
Description
ATP binding cassette subfamily D member 1
ribosomal protein SA
Image
GO Annotations
Cellular Component
Cytoplasm
Mitochondrion
Lysosome
Lysosomal Membrane
Peroxisome
Peroxisomal Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Membrane
Mitochondrial Membrane
Perinuclear Region Of Cytoplasm
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Ribosome
Plasma Membrane
Small Ribosomal Subunit
Membrane
Cytosolic Ribosome
Cytosolic Small Ribosomal Subunit
Extracellular Exosome
Ribonucleoprotein Complex
Molecular Function
Nucleotide Binding
Long-chain Fatty Acid Transmembrane Transporter Activity
Protein Binding
ATP Binding
Organophosphate Ester Transmembrane Transporter Activity
ABC-type Fatty-acyl-CoA Transporter Activity
Nucleobase-containing Compound Transmembrane Transporter Activity
Hydrolase Activity
ATP Hydrolysis Activity
Enzyme Binding
ATPase-coupled Transmembrane Transporter Activity
Identical Protein Binding
Protein Homodimerization Activity
Amide Transmembrane Transporter Activity
ADP Binding
Fatty Acyl-CoA Hydrolase Activity
Very Long-chain Fatty Acyl-CoA Hydrolase Activity
ABC-type Transporter Activity
Sulfur Compound Transmembrane Transporter Activity
Virus Receptor Activity
DNA Binding
RNA Binding
Structural Constituent Of Ribosome
Laminin Receptor Activity
Protein Binding
Ribosome Binding
Laminin Binding
Biological Process
Very Long-chain Fatty Acid Metabolic Process
Regulation Of Oxidative Phosphorylation
Fatty Acid Biosynthetic Process
Fatty Acid Beta-oxidation
Unsaturated Fatty Acid Biosynthetic Process
Peroxisome Organization
Organophosphate Ester Transport
Long-chain Fatty Acid Import Into Peroxisome
Fatty-acyl-CoA Transport
Peroxisomal Membrane Transport
Nucleobase-containing Compound Transport
Regulation Of Fatty Acid Metabolic Process
Fatty Acid Elongation
Regulation Of Fatty Acid Beta-oxidation
Positive Regulation Of Fatty Acid Beta-oxidation
Alpha-linolenic Acid Metabolic Process
Very Long-chain Fatty-acyl-CoA Catabolic Process
Long-chain Fatty Acid Catabolic Process
Long-chain Fatty Acid Biosynthetic Process
Very Long-chain Fatty Acid Catabolic Process
Amide Transport
Myelin Maintenance
Linoleic Acid Metabolic Process
Regulation Of Mitochondrial Depolarization
Transmembrane Transport
Fatty Acid Homeostasis
Sterol Homeostasis
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Regulation Of Cellular Response To Oxidative Stress
Fatty Acid Derivative Biosynthetic Process
Negative Regulation Of Reactive Oxygen Species Biosynthetic Process
Neuron Projection Maintenance
Positive Regulation Of Unsaturated Fatty Acid Biosynthetic Process
Ribosomal Small Subunit Assembly
Cytoplasmic Translation
Chromatin Remodeling
Translation
Cell Adhesion
Symbiont Entry Into Host Cell
Antiviral Innate Immune Response
Pathways
ABC transporters in lipid homeostasis
Linoleic acid (LA) metabolism
alpha-linolenic acid (ALA) metabolism
Beta-oxidation of very long chain fatty acids
Defective ABCD1 causes ALD
Class I peroxisomal membrane protein import
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
SARS-CoV-1 modulates host translation machinery
SARS-CoV-2 modulates host translation machinery
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Tigapotide
Copper
Diseases
Adrenoleukodystrophy (ALD), including: Schilder-Addison Complex; Childhood cerebral adrenoleukodystrophy (CCER); adrenomyeloneuropathy (AMN)
GWAS
Glycated hemoglobin levels (
34059833
)
Dentate gyrus volume x schizophrenia interaction (
31155012
)
Interacting Genes
5 interacting genes:
ABCD2
ABCD3
PEX19
RPSA
SLC27A2
37 interacting genes:
ABCD1
ACADVL
ACD
ANKH
CALM2
CBX5
CCDC13
CLEC4G
CSF2RA
DCTN6
EIF3E
FILNC1
GNMT
HBG2
HNRNPD
HSPB1
IL7R
ILRUN
ITGA6
KARS1
LAMA2
LINC01554
NKX3-1
OGT
PDE4B
PEA15
POT1
PRND
PROS1
RNF114
RPS21
SLC2A5
SUMO4
TINF2
TRIB3
TSC2
USP2-AS1
Entrez ID
215
3921
HPRD ID
02300
01038
Ensembl ID
ENSG00000101986
ENSG00000168028
Uniprot IDs
P33897
A0A0C4DG17
P08865
PDB IDs
7RR9
7RRA
7SHM
7SHN
7VR1
7VWC
7VX8
7VZB
7X07
7X0T
7X0Z
7X1W
7XEC
7YRQ
3BCH
4UG0
4V5Z
4V6X
5A2Q
5AJ0
5FLX
5LKS
5OA3
5T2C
5VYC
6FEC
6G18
6G4S
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6XA1
6Y0G
6Y2L
6Y57
6YBD
6YBW
6Z6L
6Z6M
6Z6N
6ZLW
6ZM7
6ZME
6ZMI
6ZMO
6ZMT
6ZMW
6ZN5
6ZOJ
6ZOK
6ZON
6ZP4
6ZUO
6ZV6
6ZVH
6ZVJ
6ZXD
6ZXE
6ZXF
6ZXG
6ZXH
7A09
7K5I
7QP6
7QP7
7QVP
7R4X
7TQL
7WTV
7WTW
7WTX
7WTZ
7WU0
7XNX
7XNY
8G5Y
8G5Z
8G60
8G61
8G6J
8GLP
8IFD
8IFE
8JDJ
8JDK
8JDL
8JDM
8K2C
8OZ0
8PJ1
8PJ2
8PJ3
8PJ4
8PJ5
8PJ6
8PPK
8PPL
8QOI
8RG0
8T4S
8UKB
8XP2
8XP3
8XSX
8XSY
8XSZ
8XXL
8XXM
8XXN
8Y0W
8Y0X
8YOO
8YOP
8ZDB
8ZDC
8ZDD
9BKD
9BLN
9C3H
9G8M
9G8O
Enriched GO Terms of Interacting Partners
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Very Long-chain Fatty Acid Catabolic Process
Peroxisomal Membrane
Long-chain Fatty Acid Transmembrane Transporter Activity
Peroxisomal Membrane Transport
Peroxisome
Peroxisome Organization
Very Long-chain Fatty Acid Metabolic Process
Long-chain Fatty Acid Transport
Fatty Acid Beta-oxidation
Long-chain Fatty Acid Import Into Peroxisome
Methyl-branched Fatty Acid Metabolic Process
Fatty Acid Oxidation
Fatty Acid Catabolic Process
Lipid Oxidation
Fatty Acid Transport
Long-chain Fatty Acid Metabolic Process
Monocarboxylic Acid Transport
Fatty Acyl-CoA Hydrolase Activity
Lipid Modification
Bile Acid Biosynthetic Process
Carboxylic Acid Catabolic Process
ATPase-coupled Transmembrane Transporter Activity
Bile Acid Metabolic Process
Intracellular Lipid Transport
Carboxylic Acid Transport
Organic Acid Transport
Carboxylic Acid Biosynthetic Process
Lipid Catabolic Process
ABC-type Transporter Activity
Fatty Acid Metabolic Process
Lipid Transport
Fatty Acid Derivative Biosynthetic Process
Organic Anion Transport
Intracellular Transport
Fatty Acid Derivative Metabolic Process
Small Molecule Biosynthetic Process
Negative Regulation Of Lipid Binding
Peroxisome Membrane Class-1 Targeting Sequence Binding
Monocarboxylic Acid Metabolic Process
Lipid Biosynthetic Process
Fatty Acid Biosynthetic Process
Organophosphate Ester Transmembrane Transporter Activity
Nucleobase-containing Compound Transmembrane Transporter Activity
Carboxylic Acid Transmembrane Transport
Peroxisome Membrane Targeting Sequence Binding
Phytanic Acid Metabolic Process
Pristanate-CoA Ligase Activity
Phytanate-CoA Ligase Activity
Cholate-CoA Ligase Activity
Organic Acid Transmembrane Transport
Telomere Assembly
Shelterin Complex
Telomeric DNA Binding
Nuclear Telomere Cap Complex
Regulation Of Telomere Maintenance Via Telomerase
Telomere Capping
Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance
Regulation Of DNA Biosynthetic Process
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Chromosome Organization
Regulation Of Telomere Maintenance
Regulation Of Translational Initiation
Fructose Binding
Telomerase Inhibitor Activity
Negative Regulation Of Telomere Maintenance
Establishment Of Protein Localization To Telomere
Regulation Of Fatty Acid Biosynthetic Process
Negative Regulation Of Translational Initiation
Negative Regulation Of Biosynthetic Process
Response To Sodium Phosphate
Protein Localization To Chromosome, Telomeric Region
Positive Regulation Of Translation
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Insulin Receptor Signaling Pathway
Chromosome, Telomeric Region
Urogenital System Development
Regulation Of Small Molecule Metabolic Process
Negative Regulation Of Chromosome Organization
Negative Regulation Of DNA Binding
Regulation Of Lipid Biosynthetic Process
Negative Regulation Of Fatty Acid Biosynthetic Process
Translation
Telomere Maintenance Via Telomerase
Negative Regulation Of Metabolic Process
Regulation Of Fatty Acid Metabolic Process
Positive Regulation Of Telomere Maintenance Via Telomerase
Response To Salt
Regulation Of T Cell Differentiation In Thymus
RNA-templated DNA Biosynthetic Process
Telomere Maintenance
Very Long-chain Fatty-acyl-CoA Catabolic Process
Negative Regulation Of Macromolecule Metabolic Process
ABC-type Fatty-acyl-CoA Transporter Activity
Hepatocyte Dedifferentiation
Regulation Of Translation
Positive Regulation Of Telomere Maintenance Via Telomere Lengthening
Cellular Response To Putrescine
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