ABCD1 and ABCD3

Number of citations of the paper that reports this interaction (PMID 22939629)
44

Data Source:
BioGRID (two hybrid, biochemical)
HPRD (two hybrid, in vivo)

		ABCD1	ABCD3
Gene Name		ATP-binding cassette, sub-family D (ALD), member 1	ATP-binding cassette, sub-family D (ALD), member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Cytosol Membrane Perinuclear Region Of Cytoplasm	Mitochondrial Inner Membrane Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Transporter Activity Peroxisomal Fatty-acyl-CoA Transporter Activity Protein Binding ATP Binding ATPase Activity Enzyme Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances Identical Protein Binding Protein Homodimerization Activity	Protein Binding ATP Binding ATPase Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Protein Homodimerization Activity
	Biological Process	Fatty Acid Beta-oxidation Peroxisome Organization Peroxisomal Long-chain Fatty Acid Import Peroxisomal Membrane Transport Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Unsaturated Fatty Acid Metabolic Process Alpha-linolenic Acid Metabolic Process Long-chain Fatty Acid Catabolic Process Very Long-chain Fatty Acid Catabolic Process Linoleic Acid Metabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Transmembrane Transport	Fatty Acid Beta-oxidation Peroxisome Organization Very Long-chain Fatty Acid Catabolic Process Transmembrane Transport
Pathways		alpha-linolenic acid (ALA) metabolism ABC-family proteins mediated transport Metabolism of lipids and lipoproteins alpha-linolenic (omega3) and linoleic (omega6) acid metabolism Linoleic acid (LA) metabolism Beta-oxidation of very long chain fatty acids ABCA transporters in lipid homeostasis Peroxisomal lipid metabolism	ABC-family proteins mediated transport ABCA transporters in lipid homeostasis
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ABCD2 ABCD3 PEX19 RPSA SLC27A2	6 interactors: ABCD1 ABCD2 COL6A2 PEX19 PSMA1 TUFT1
Entrez ID		215	5825
HPRD ID		02300	01368
Ensembl ID		ENSG00000101986	ENSG00000117528
Uniprot IDs		P33897	E7EUE1 P28288
PDB IDs
Enriched GO Terms of Interacting Partners?		Very Long-chain Fatty Acid Catabolic Process Very Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Cellular Lipid Catabolic Process Lipid Modification Carboxylic Acid Catabolic Process Lipid Catabolic Process Fatty Acid Metabolic Process Peroxisome Organization Monocarboxylic Acid Metabolic Process Catabolic Process Negative Regulation Of Lipid Binding Methyl-branched Fatty Acid Metabolic Process RRNA Export From Nucleus Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Transport Protein Targeting To Membrane Cellular Lipid Metabolic Process Carboxylic Acid Metabolic Process Peroxisome Membrane Biogenesis Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Establishment Of Protein Localization To Membrane RRNA Transport Organic Acid Metabolic Process RRNA 3'-end Processing Fatty Acid Alpha-oxidation Long-chain Fatty Acid Import Lipid Metabolic Process Protein Import Into Peroxisome Membrane Chaperone-mediated Protein Transport Peroxisomal Membrane Transport Establishment Of Protein Localization To Organelle Ribosomal Small Subunit Assembly Positive Regulation Of Fatty Acid Beta-oxidation Protein Localization To Membrane Oxidation-reduction Process Peroxisome Fission Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Protein Targeting Maturation Of 5.8S RRNA Transmembrane Transport Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Protein Localization To Organelle Bile Acid Biosynthetic Process Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Protein Targeting To Peroxisome	Very Long-chain Fatty Acid Catabolic Process Peroxisomal Membrane Transport Very Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Peroxisome Organization Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Negative Regulation Of Lipid Binding Peroxisomal Long-chain Fatty Acid Import Catabolic Process Cellular Lipid Catabolic Process Peroxisome Membrane Biogenesis Lipid Modification Carboxylic Acid Catabolic Process Lipid Catabolic Process Protein Import Into Peroxisome Membrane Chaperone-mediated Protein Transport Long-chain Fatty Acid Catabolic Process Alpha-linolenic Acid Metabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Fatty Acid Metabolic Process Linoleic Acid Metabolic Process Positive Regulation Of Fatty Acid Beta-oxidation Peroxisome Fission Protein Heterotrimerization Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Regulation Of Cellular Ketone Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Positive Regulation Of Lipid Catabolic Process Membrane Biogenesis Transmembrane Transport Monocarboxylic Acid Metabolic Process Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Fatty Acid Oxidation Protein Trimerization
Tagcloud ?		abcd4 belonging cassette cho eukaryotes fungi gfp h0 homologs hydropathy hydrophobic lacking localization lost mammals metazoan motif nh2 organelle peroxisomes plot possesses possessing segment subcellular subfamily terminal	200nm acyl adipogenesis adipose anabolic associate cassette catabolic catalase centrifugation coas compartment d2 dense homogenates immunoisolation microperoxisome microscopic organelle organelles peroxisome peroxisomes pex19 physically proteome proteomic scarcity transporter
Tagcloud (Difference) ?		abcd4 belonging cho eukaryotes fungi gfp h0 homologs hydropathy hydrophobic lacking localization lost mammals metazoan motif nh2 plot possesses possessing segment subcellular subfamily terminal	200nm acyl adipogenesis adipose anabolic associate catabolic catalase centrifugation coas compartment d2 dense homogenates immunoisolation microperoxisome microscopic organelles peroxisome pex19 physically proteome proteomic scarcity transporter
Tagcloud (Intersection) ?		cassette organelle peroxisomes