RPSA and LAMA2

Number of citations of the paper that reports this interaction (PubMedID 11054877)
0

Data Source:
HPRD (in vitro)

		RPSA	LAMA2
Description		ribosomal protein SA	laminin subunit alpha 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Ribosome Plasma Membrane Small Ribosomal Subunit Membrane Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Extracellular Exosome Ribonucleoprotein Complex	Extracellular Region Basement Membrane Extracellular Matrix Neuromuscular Junction Sarcolemma Synaptic Cleft Dendritic Spine Protein Complex Involved In Cell-matrix Adhesion
	Molecular Function	Virus Receptor Activity DNA Binding RNA Binding Structural Constituent Of Ribosome Laminin Receptor Activity Protein Binding Ribosome Binding Laminin Binding	Signaling Receptor Binding Structural Molecule Activity Extracellular Matrix Structural Constituent
	Biological Process	Ribosomal Small Subunit Assembly Cytoplasmic Translation Chromatin Remodeling Translation Cell Adhesion Symbiont Entry Into Host Cell Antiviral Innate Immune Response	Cell Adhesion Axon Guidance Muscle Organ Development Schwann Cell Differentiation Regulation Of Cell Adhesion Regulation Of Cell Migration Positive Regulation Of Synaptic Transmission, Cholinergic Maintenance Of Blood-brain Barrier Positive Regulation Of Cell Adhesion Regulation Of Embryonic Development Positive Regulation Of Muscle Cell Differentiation Regulation Of Basement Membrane Organization Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans MET activates PTK2 signaling EGR2 and SOX10-mediated initiation of Schwann cell myelination Attachment of bacteria to epithelial cells Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC) Developmental Lineage of Pancreatic Ductal Cells
Drugs		Tigapotide Copper
Diseases			Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
GWAS		Dentate gyrus volume x schizophrenia interaction ( 31155012)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Appendicular lean mass ( 33097823) Axial length ( 24144296) Body mass index ( 20397748) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Height ( 31562340) High myopia ( 33830181 31816047) Hyperopia ( 25233373 33830181) Low myopia vs hyperopia ( 33830181) Metabolite levels ( 23823483) Myopia ( 25233373 27182965) Night sleep phenotypes ( 27126917) Periodontal disease-related phenotype (Socransky) ( 24347629) Refractive error ( 23396134) Retinal detachment or retinal break ( 31816047) Serum bilirubin levels x Mediterranean diet adherence interaction in metabolic syndrome ( 30621171) Sleep duration (short sleep) ( 30846698) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Tea consumption ( 31046077)
Interacting Genes		37 interacting genes: ABCD1 ACADVL ACD ANKH CALM2 CBX5 CCDC13 CLEC4G CSF2RA DCTN6 EIF3E FILNC1 GNMT HBG2 HNRNPD HSPB1 IL7R ILRUN ITGA6 KARS1 LAMA2 LINC01554 NKX3-1 OGT PDE4B PEA15 POT1 PRND PROS1 RNF114 RPS21 SLC2A5 SUMO4 TINF2 TRIB3 TSC2 USP2-AS1	4 interacting genes: DAG1 RPSA SNAPIN TRIM63
Entrez ID		3921	3908
HPRD ID		01038	01125
Ensembl ID		ENSG00000168028	ENSG00000196569
Uniprot IDs		A0A0C4DG17 P08865	A0A087WYF1 P24043 Q59H37
PDB IDs		3BCH 4UG0 4V5Z 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6FEC 6G18 6G4S 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZUO 6ZV6 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I 7QP6 7QP7 7QVP 7R4X 7TQL 7WTV 7WTW 7WTX 7WTZ 7WU0 7XNX 7XNY 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8PPL 8QOI 8RG0 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 8ZDC 8ZDD 9BKD 9BLN 9C3H 9G8M 9G8O	4YEP 4YEQ
Enriched GO Terms of Interacting Partners?		Telomere Assembly Shelterin Complex Telomeric DNA Binding Nuclear Telomere Cap Complex Regulation Of Telomere Maintenance Via Telomerase Telomere Capping Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Regulation Of Translational Initiation Fructose Binding Telomerase Inhibitor Activity Negative Regulation Of Telomere Maintenance Establishment Of Protein Localization To Telomere Regulation Of Fatty Acid Biosynthetic Process Negative Regulation Of Translational Initiation Negative Regulation Of Biosynthetic Process Response To Sodium Phosphate Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Insulin Receptor Signaling Pathway Chromosome, Telomeric Region Urogenital System Development Regulation Of Small Molecule Metabolic Process Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Binding Regulation Of Lipid Biosynthetic Process Negative Regulation Of Fatty Acid Biosynthetic Process Translation Telomere Maintenance Via Telomerase Negative Regulation Of Metabolic Process Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Telomere Maintenance Via Telomerase Response To Salt Regulation Of T Cell Differentiation In Thymus RNA-templated DNA Biosynthetic Process Telomere Maintenance Very Long-chain Fatty-acyl-CoA Catabolic Process Negative Regulation Of Macromolecule Metabolic Process ABC-type Fatty-acyl-CoA Transporter Activity Hepatocyte Dedifferentiation Regulation Of Translation Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Cellular Response To Putrescine	Laminin Binding Muscle Attachment Symbiont Entry Into Host Cell Virus Receptor Activity Positive Regulation Of Late Endosome To Lysosome Transport Calcium-dependent Cell-matrix Adhesion Biological Process Involved In Interaction With Host Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Retrograde Trans-synaptic Signaling By Trans-synaptic Protein Complex Nerve Maturation Developmental Maturation Protein Metabolic Process Laminin Receptor Activity Response To Denervation Involved In Regulation Of Muscle Adaptation Trans-synaptic Signaling By Trans-synaptic Complex Laminin-1 Binding Schwann Cell Differentiation Photoreceptor Ribbon Synapse Dystroglycan Complex Contractile Ring Terminal Button Organization Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Response To Muscle Inactivity Synaptic Vesicle Maturation Regulation Of Lysosome Size BORC Complex Microvesicle Muscle Atrophy Dystroglycan Binding Trans-synaptic Signaling Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Branching Involved In Salivary Gland Morphogenesis Costamere Vinculin Binding Cellular Response To Sterol Dystrophin-associated Glycoprotein Complex Neuron Projection Development Node Of Ranvier Schwann Cell Development Nuclear Periphery Skeletal Muscle Tissue Regeneration Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Commissural Neuron Axon Guidance Angiogenesis Involved In Wound Healing Axon Regeneration Morphogenesis Of An Epithelial Sheet Positive Regulation Of Myelination Alpha-actinin Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?