EPHA5 and EFNA2

Number of citations of the paper that reports this interaction (PMID 10531456)
13

Data Source:
HPRD (in vivo)

		EPHA5	EFNA2
Gene Name		EPH receptor A5	ephrin-A2
Image
Gene Ontology Annotations	Cellular Component	Rough Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Axon Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm	Extracellular Region Plasma Membrane Anchored Component Of Membrane Neuromuscular Junction Perikaryon
	Molecular Function	Ephrin Receptor Activity GPI-linked Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity ATP Binding	Ephrin Receptor Binding
	Biological Process	Axon Guidance Peptidyl-tyrosine Phosphorylation CAMP-mediated Signaling Hippocampus Development Regulation Of Rac GTPase Activity Positive Regulation Of CREB Transcription Factor Activity Regulation Of Actin Cytoskeleton Organization Ephrin Receptor Signaling Pathway Neuron Development Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus	Cell-cell Signaling Axon Guidance Olfactory Bulb Development Osteoclast Differentiation Bone Remodeling Ephrin Receptor Signaling Pathway
Pathways		EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling	EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		HIV-1 viral setpoint ( 22174851)
Protein-Protein Interactions		6 interactors: EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 NEDD4	6 interactors: ADAM10 EPHA2 EPHA3 EPHA5 RUNX1 ZHX1
Entrez ID		2044	1943
HPRD ID		02474	04132
Ensembl ID		ENSG00000145242	ENSG00000099617
Uniprot IDs		B7ZKJ3 B7ZKW7 F8VP57 F8W9W0 P54756 Q59FT4	O43921
PDB IDs		2R2P 4ET7	2WO3
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Neuron Projection Development Neuron Development Axon Guidance Neuron Differentiation Cell Projection Organization Locomotion Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Generation Of Neurons Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurogenesis Cell Morphogenesis Involved In Differentiation Cell Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Nervous System Development Cell Morphogenesis Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Cell Differentiation Response To External Stimulus Cell-cell Signaling System Development Osteoclast Differentiation Multicellular Organismal Development Anatomical Structure Development Bone Remodeling Signal Transduction Regulation Of Dendrite Morphogenesis Developmental Process Signaling Cell Communication Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Dendrite Development Tissue Remodeling Myeloid Leukocyte Differentiation Cellular Response To Stimulus Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Dendritic Spine Morphogenesis Endocardial Cushion To Mesenchymal Transition Involved In Heart Valve Formation Mesenchyme Development Regulation Of Peptidyl-tyrosine Phosphorylation	Ephrin Receptor Signaling Pathway Neuron Development Axon Guidance Neuron Differentiation Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Generation Of Neurons Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Differentiation Neurogenesis Cell Morphogenesis Involved In Differentiation Cell Development Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Rho GTPase Activity Peptidyl-tyrosine Phosphorylation Nervous System Development Regulation Of Rho Protein Signal Transduction Cell Morphogenesis Anatomical Structure Morphogenesis Cell Projection Organization Locomotion Protein Phosphorylation Developmental Process Movement Of Cell Or Subcellular Component Regulation Of Ras GTPase Activity Notochord Cell Development Constitutive Protein Ectodomain Proteolysis Regulation Of Cell Adhesion Regulation Of Ras Protein Signal Transduction Response To External Stimulus Positive Regulation Of Progesterone Secretion Phosphorylation Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Cellular Component Organization Regulation Of GTPase Activity Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching PMA-inducible Membrane Protein Ectodomain Proteolysis Axial Mesoderm Formation Regulation Of Progesterone Secretion System Development Regulation Of Hair Follicle Cell Proliferation Peptidyl-amino Acid Modification Notochord Formation
Tagcloud ?		aurka aurkb bioinformatics cdkn2a copy custom describing flt4 frameshift insertions interrogating kdm6a leiomyosarcomas locally losses map2k4 multiplexed nf1 ngs notch1 pdgfrb pik3ca pipeline rationale rb1 sarcomas soft stratification targetable	16p13 16q12 19p13 21q21 affymetrix agar arrays cd133 cd133high cd133low colonies die extracranial gains genotyping heterozygosity il2rgammac initiating injections lethal nb neurosphere neurospheres orthotopic persist relapses soft tics uncontrolled
Tagcloud (Difference) ?		aurka aurkb bioinformatics cdkn2a copy custom describing flt4 frameshift insertions interrogating kdm6a leiomyosarcomas locally losses map2k4 multiplexed nf1 ngs notch1 pdgfrb pik3ca pipeline rationale rb1 sarcomas stratification targetable	16p13 16q12 19p13 21q21 affymetrix agar arrays cd133 cd133high cd133low colonies die extracranial gains genotyping heterozygosity il2rgammac initiating injections lethal nb neurosphere neurospheres orthotopic persist relapses tics uncontrolled
Tagcloud (Intersection) ?		soft