ENO3 and TRAPPC2

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		ENO3	TRAPPC2
Description		enolase 3	trafficking protein particle complex subunit 2
Image			No pdb structure
GO Annotations	Cellular Component	Phosphopyruvate Hydratase Complex Extracellular Space Cytoplasm Cytosol Plasma Membrane Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm TRAPPII Protein Complex TRAPPIII Protein Complex
	Molecular Function	Magnesium Ion Binding Phosphopyruvate Hydratase Activity Protein Binding Lyase Activity Metal Ion Binding	Protein Binding Transmembrane Transporter Binding
	Biological Process	Gluconeogenesis Glycolytic Process Canonical Glycolysis	Skeletal System Development Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Vesicle-mediated Transport COPII Vesicle Coating Vesicle Tethering
Pathways		Glycolysis Gluconeogenesis	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		2-phospho-D-glyceric acid Phosphoenolpyruvate 2-Phosphoglycolic Acid Phosphonoacetohydroxamic Acid
Diseases			Spondyloepiphyseal dysplasia tarda
GWAS		Keratoconus ( 33649486) Red cell distribution width ( 32888494)
Interacting Genes		20 interacting genes: ALDOA APP DCTN1 DSP HSPB2 KALRN LINC01554 MAN2A2 MTMR14 NEB PGM1 PKM PNKD SGCG SNAPIN SPTB TCAP TRAPPC2 TRIM63 TTN	34 interacting genes: ABRA CLIC1 CLIC2 DAPK1 EIF3C ENO1 ENO3 EPS15L1 HLA-E INCA1 KCTD1 MBD3L1 MFHAS1 NICN1 NME4 NR5A1 PITX1 PYGM REPS1 SLC25A35 SNAPC5 SNCA TEPSIN TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9 UQCC2 ZBTB38 ZNF438 ZNF655 ZRANB1
Entrez ID		2027	6399
HPRD ID		11746	02189
Ensembl ID		ENSG00000108515	ENSG00000196459
Uniprot IDs		P13929	P0DI81 P0DI82 Q6IBE5
PDB IDs		2XSX
Enriched GO Terms of Interacting Partners?		M Band I Band Titin-telethonin Complex Skeletal Muscle Myosin Thick Filament Assembly Sarcomerogenesis Cytoplasm Somatic Muscle Development Myosin Filament Assembly Actin Cytoskeleton Supramolecular Fiber Organization Z Disc Structural Constituent Of Muscle Skeletal Muscle Thin Filament Assembly Glycolytic Process ADP Catabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Detection Of Muscle Stretch Hexose Metabolic Process Ribonucleoside Diphosphate Catabolic Process ADP Metabolic Process Nucleoside Diphosphate Catabolic Process Cardiac Muscle Tissue Morphogenesis Monosaccharide Metabolic Process Pyruvate Metabolic Process Muscle Contraction Muscle Tissue Morphogenesis Ribonucleoside Diphosphate Metabolic Process Neuron Projection Maintenance Contractile Muscle Fiber Titin Binding Purine Ribonucleotide Catabolic Process Axo-dendritic Transport Striated Muscle Contraction Nucleoside Diphosphate Metabolic Process Purine Nucleotide Catabolic Process System Process Cardiac Myofibril Assembly Muscle Filament Sliding Actin-myosin Filament Sliding Muscle System Process Actin Filament Organization Nucleotide Catabolic Process Nicotinamide Nucleotide Metabolic Process Carbohydrate Catabolic Process Cardiac Muscle Hypertrophy Ficolin-1-rich Granule Lumen Response To Muscle Stretch Nucleoside Phosphate Catabolic Process Cytosol Muscle Hypertrophy	TRAPP Complex Vesicle Tethering TRAPPII Protein Complex Vesicle Coating Endoplasmic Reticulum To Golgi Vesicle-mediated Transport TRAPPIII Protein Complex Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity COPII Vesicle Coating Golgi Vesicle Transport Protein Binding Cis-Golgi Network Membrane Vesicle-mediated Transport Vesicle Organization Intracellular Transport Establishment Of Localization In Cell
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