ENO3 and PGM1

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		ENO3	PGM1
Description		enolase 3	phosphoglucomutase 1
Image
GO Annotations	Cellular Component	Phosphopyruvate Hydratase Complex Extracellular Space Cytoplasm Cytosol Plasma Membrane Membrane Extracellular Exosome	Extracellular Region Cytoplasm Cytosol Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Magnesium Ion Binding Phosphopyruvate Hydratase Activity Protein Binding Lyase Activity Metal Ion Binding	Magnesium Ion Binding Phosphoglucomutase Activity Protein Binding Isomerase Activity Intramolecular Phosphotransferase Activity Metal Ion Binding
	Biological Process	Gluconeogenesis Glycolytic Process Canonical Glycolysis	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Galactose Catabolic Process Via UDP-galactose, Leloir Pathway
Pathways		Glycolysis Gluconeogenesis	Glycogen synthesis Defective PGM1 causes PGM1-CDG Neutrophil degranulation Glycogen breakdown (glycogenolysis) Galactose catabolism
Drugs		2-phospho-D-glyceric acid Phosphoenolpyruvate 2-Phosphoglycolic Acid Phosphonoacetohydroxamic Acid	Alpha-D-Glucose 1,6-Bisphosphate Alpha-D-Glucose-1-Phosphate-6-Vanadate
Diseases
GWAS		Keratoconus ( 33649486) Red cell distribution width ( 32888494)	Alcohol consumption (transferrin glycosylation) ( 21665994) Type 1 diabetes ( 19430480 32005708 33830302 34012112 34127860) Type 2 diabetes ( 32499647)
Interacting Genes		20 interacting genes: ALDOA APP DCTN1 DSP HSPB2 KALRN LINC01554 MAN2A2 MTMR14 NEB PGM1 PKM PNKD SGCG SNAPIN SPTB TCAP TRAPPC2 TRIM63 TTN	19 interacting genes: APP DNAJB6 DYRK3 ENO3 HSPB2 KIF1B LINC01554 NLRP3 OGT PAXIP1 PEA15 POT1 S100A1 S100B TERF1 TERF2IP TINF2 TMEM132D USP4
Entrez ID		2027	5236
HPRD ID		11746	01389
Ensembl ID		ENSG00000108515	ENSG00000079739
Uniprot IDs		P13929	B4DDQ8 B7Z6C2 P36871
PDB IDs		2XSX	5EPC 5F9C 5HSH 5JN5 5TR2 5VBI 5VEC 5VG7 5VIN 6SNO 6SNP 6SNQ 6UIQ 6UO6 7S0W 7S77
Enriched GO Terms of Interacting Partners?		M Band I Band Titin-telethonin Complex Skeletal Muscle Myosin Thick Filament Assembly Sarcomerogenesis Cytoplasm Somatic Muscle Development Myosin Filament Assembly Actin Cytoskeleton Supramolecular Fiber Organization Z Disc Structural Constituent Of Muscle Skeletal Muscle Thin Filament Assembly Glycolytic Process ADP Catabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Detection Of Muscle Stretch Hexose Metabolic Process Ribonucleoside Diphosphate Catabolic Process ADP Metabolic Process Nucleoside Diphosphate Catabolic Process Cardiac Muscle Tissue Morphogenesis Monosaccharide Metabolic Process Pyruvate Metabolic Process Muscle Contraction Muscle Tissue Morphogenesis Ribonucleoside Diphosphate Metabolic Process Neuron Projection Maintenance Contractile Muscle Fiber Titin Binding Purine Ribonucleotide Catabolic Process Axo-dendritic Transport Striated Muscle Contraction Nucleoside Diphosphate Metabolic Process Purine Nucleotide Catabolic Process System Process Cardiac Myofibril Assembly Muscle Filament Sliding Actin-myosin Filament Sliding Muscle System Process Actin Filament Organization Nucleotide Catabolic Process Nicotinamide Nucleotide Metabolic Process Carbohydrate Catabolic Process Cardiac Muscle Hypertrophy Ficolin-1-rich Granule Lumen Response To Muscle Stretch Nucleoside Phosphate Catabolic Process Cytosol Muscle Hypertrophy	Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Telomeric DNA Binding Negative Regulation Of Telomere Maintenance G-rich Strand Telomeric DNA Binding Positive Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization RNA-templated DNA Biosynthetic Process Chorion Development Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Telomere Assembly Telomere Organization Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Telomeric D-loop Disassembly Chromosome, Telomeric Region Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Telomeric Loop Disassembly Protein Localization To Chromosome, Telomeric Region RAGE Receptor Binding Negative Regulation Of Macromolecule Biosynthetic Process S100 Protein Binding Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Nucleoplasm Negative Regulation Of Cellular Component Organization Regulation Of DNA Biosynthetic Process DNA Biosynthetic Process DNA Metabolic Process Regulation Of Chromosome Organization Regulation Of TORC1 Signaling Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of DNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Unfolded Protein Binding Regulation Of Cellular Response To Stress Identical Protein Binding Chromosome Organization
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