ZNF385C and SPAG5

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		ZNF385C	SPAG5
Description		zinc finger protein 385C	sperm associated antigen 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromosome, Centromeric Region Kinetochore Spindle Pole Chromosome Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule Nuclear Body Midbody Centriolar Satellite Ciliary Rootlet Microtubule Plus-end Ciliary Basal Body Mitotic Spindle Mitotic Spindle Pole
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Microtubule Binding
	Biological Process		Mitotic Sister Chromatid Segregation Spindle Organization Chromosome Segregation Positive Regulation Of Intracellular Transport Establishment Of Spindle Orientation Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Protein Localization To Centrosome Regulation Of Metaphase Plate Congression Positive Regulation Of Spindle Assembly
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)
Interacting Genes		15 interacting genes: BOLL HNRNPK PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 RBM47 RBMY1F RBPMS RBPMS2 SPAG5 SRSF11 THAP1	59 interacting genes: AIRIM AMOTL2 ARNT2 ATN1 BARD1 CCDC33 CCHCR1 CDC20B CDK1 CENPH CHCHD3 DCLRE1B DCX EIF4E2 EIF4ENIF1 ENKD1 FBXO28 FMR1 GEM GOLGA8EP GOLGA8F HAUS1 IGFN1 IQCE KANSL1 KRT3 KRT75 LGALS14 LINGO1 MID1 MID2 NEBL NLGN3 ODF1 ORC6 PIMREG PKN1 PLK4 POLR2L POM121 RBM41 SH2D4A SHANK3 SMARCA2 SMARCE1 SNAP47 SNAPIN SPAG5-AS1 TSC1 TSHZ3 TTC23 ZC2HC1C ZFC3H1 ZFYVE26 ZGPAT ZMAT2 ZNF385C ZNF572 ZNF688
Entrez ID		201181	10615
HPRD ID		13245	10246
Ensembl ID		ENSG00000187595	ENSG00000076382
Uniprot IDs		A0A8I5KWL9	Q96R06
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process Nucleic Acid Binding Regulation Of RNA Splicing Regulation Of Alternative MRNA Splicing, Via Spliceosome Identical Protein Binding MRNA Binding Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process RNA Binding 3'-UTR-mediated MRNA Stabilization MRNA 3'-UTR Binding RNA Splicing MRNA Processing RNA Processing MRNA Metabolic Process MRNA Stabilization Negative Regulation Of MRNA Catabolic Process RNA Stabilization
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