SPAG5 and ZFYVE26

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		SPAG5	ZFYVE26
Description		sperm associated antigen 5	zinc finger FYVE-type containing 26
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Spindle Pole Chromosome Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule Nuclear Body Midbody Centriolar Satellite Ciliary Rootlet Microtubule Plus-end Ciliary Basal Body Mitotic Spindle Mitotic Spindle Pole	Cytoplasm Lysosome Lysosomal Membrane Early Endosome Late Endosome Centrosome Cytoskeleton Midbody
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Zinc Ion Binding Lipid Binding Protein Kinase Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding
	Biological Process	Mitotic Sister Chromatid Segregation Spindle Organization Chromosome Segregation Positive Regulation Of Intracellular Transport Establishment Of Spindle Orientation Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Protein Localization To Centrosome Regulation Of Metaphase Plate Congression Positive Regulation Of Spindle Assembly	Mitotic Cytokinesis Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Damage Response Lysosome Organization Regulation Of Cytokinesis Cell Division Autophagosome Organization
Pathways
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS			Amyotrophic lateral sclerosis (sporadic) ( 24529757) Asthma ( 31959851) Asthma (childhood onset) ( 31036433)
Interacting Genes		59 interacting genes: AIRIM AMOTL2 ARNT2 ATN1 BARD1 CCDC33 CCHCR1 CDC20B CDK1 CENPH CHCHD3 DCLRE1B DCX EIF4E2 EIF4ENIF1 ENKD1 FBXO28 FMR1 GEM GOLGA8EP GOLGA8F HAUS1 IGFN1 IQCE KANSL1 KRT3 KRT75 LGALS14 LINGO1 MID1 MID2 NEBL NLGN3 ODF1 ORC6 PIMREG PKN1 PLK4 POLR2L POM121 RBM41 SH2D4A SHANK3 SMARCA2 SMARCE1 SNAP47 SNAPIN SPAG5-AS1 TSC1 TSHZ3 TTC23 ZC2HC1C ZFC3H1 ZFYVE26 ZGPAT ZMAT2 ZNF385C ZNF572 ZNF688	36 interacting genes: ALAS1 ASB15 CBY2 CCDC125 CCDC136 CEP44 CFTR GOLGA2 GPRASP2 HMBOX1 HNRNPC HOOK2 KRT15 KRT27 KRT34 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAGED1 MDFI PLEKHF2 PNMA1 PNMA5 PPP1R16A PRDM6 SPAG5 SSX2IP TADA2A TCEANC TDO2 TFIP11 TRAF1 TTC23 USHBP1 USP20
Entrez ID		10615	23503
HPRD ID		10246	15734
Ensembl ID		ENSG00000076382	ENSG00000072121
Uniprot IDs		Q96R06	Q68DK2
PDB IDs
Enriched GO Terms of Interacting Partners?			Keratin Filament Intermediate Filament Identical Protein Binding Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Centrosome Cycle
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