SPAG5 and CDC20B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SPAG5	CDC20B
Description		sperm associated antigen 5	cell division cycle 20B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Spindle Pole Chromosome Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule Nuclear Body Midbody Centriolar Satellite Ciliary Rootlet Microtubule Plus-end Ciliary Basal Body Mitotic Spindle Mitotic Spindle Pole	Anaphase-promoting Complex Cytoplasm Deuterosome
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Anaphase-promoting Complex Binding Ubiquitin-protein Transferase Activator Activity Ubiquitin Ligase Activator Activity
	Biological Process	Mitotic Sister Chromatid Segregation Spindle Organization Chromosome Segregation Positive Regulation Of Intracellular Transport Establishment Of Spindle Orientation Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Protein Localization To Centrosome Regulation Of Metaphase Plate Congression Positive Regulation Of Spindle Assembly	Anaphase-promoting Complex-dependent Catabolic Process De Novo Centriole Assembly Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process
Pathways
Drugs
Diseases
GWAS			Cocaine dependence ( 31212010)
Interacting Genes		59 interacting genes: AIRIM AMOTL2 ARNT2 ATN1 BARD1 CCDC33 CCHCR1 CDC20B CDK1 CENPH CHCHD3 DCLRE1B DCX EIF4E2 EIF4ENIF1 ENKD1 FBXO28 FMR1 GEM GOLGA8EP GOLGA8F HAUS1 IGFN1 IQCE KANSL1 KRT3 KRT75 LGALS14 LINGO1 MID1 MID2 NEBL NLGN3 ODF1 ORC6 PIMREG PKN1 PLK4 POLR2L POM121 RBM41 SH2D4A SHANK3 SMARCA2 SMARCE1 SNAP47 SNAPIN SPAG5-AS1 TSC1 TSHZ3 TTC23 ZC2HC1C ZFC3H1 ZFYVE26 ZGPAT ZMAT2 ZNF385C ZNF572 ZNF688	21 interacting genes: CCDC57 FHL5 GEMIN4 GOLGA2 KANK2 KRT31 KRT34 KRT40 MAGEA11 MDFI MTUS2 NUTM1 PLEKHF2 PLK2 SPAG5 TACC3 TRAF2 TRIM23 TRIM27 TRIM37 VPS52
Entrez ID		10615	166979
HPRD ID		10246	13428
Ensembl ID		ENSG00000076382	ENSG00000164287
Uniprot IDs		Q96R06	Q86Y33
PDB IDs
Enriched GO Terms of Interacting Partners?			Spindle Organization Cytoskeleton Organization Spindle Pole Cytoskeleton Structural Constituent Of Skin Epidermis Intermediate Filament Organization Mitotic Spindle Organization Microtubule Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Ubiquitin-protein Transferase Activity Regulation Of Microtubule-based Process Establishment Of Localization In Cell Intracellular Transport Organelle Organization Regulation Of Cytoskeleton Organization Regulation Of Centriole Replication Microtubule Cytoskeleton Organization Involved In Mitosis Centriolar Satellite Mitotic Spindle Microtubule Nucleation Tumor Necrosis Factor Receptor Binding Ubiquitin Protein Ligase Activity Mitotic Cell Cycle Phase Transition Regulation Of Autophagy Intermediate Filament Cell Cycle Phase Transition Centrosome Positive Regulation Of Autophagy Embryonic Ectodermal Digestive Tract Development TORC2 Complex Disassembly Structural Molecule Activity Regulation Of Cell Cycle Cellular Localization Regulation Of Centrosome Duplication Regulation Of Cell Cycle Process Syntaxin Binding Microtubule-based Process Regulation Of Centrosome Cycle Regulation Of Organelle Organization TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Negative Regulation Of Vitamin D Receptor Signaling Pathway Supramolecular Fiber Organization Spindle Microtubule Binding Protein Autoubiquitination Regulation Of Organelle Assembly
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