SPAG5 and IQCE

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		SPAG5	IQCE
Gene Name		sperm associated antigen 5	IQ motif containing E
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Midbody Microtubule Plus-end Mitotic Spindle	Primary Cilium
	Molecular Function	Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Spindle Organization Chromosome Segregation Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Pathways			Hedgehog 'on' state Signaling by Hedgehog Activation of SMO
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: AMOTL2 ARNT2 ATN1 BARD1 C1orf109 CCDC33 CCHCR1 CDC20B CDK1 CHCHD3 DCX EIF4E2 EIF4ENIF1 FBXO28 FMR1 GOLGA8EP GOLGA8F HAUS1 IQCE KANSL1 LGALS14 LINGO1 ODF1 ORC6 POLR2L RBM41 SH2D4A SMARCE1 SNAP47 SNAPIN TSHZ3 TTC23 ZC2HC1C ZFC3H1 ZMAT2	14 interactors: CALM2 CALM3 CARD9 CEP70 GOLGA2 HOOK2 LZTS2 MTUS2 PSMA3 RPGRIP1 SPAG5 TRIM23 TRIM27 TTC23L
Entrez ID		10615	23288
HPRD ID		10246	11050
Ensembl ID		ENSG00000076382	ENSG00000106012
Uniprot IDs		Q96R06	B4DXN1 Q6IPM2
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Fusion Negative Regulation Of Gene Expression Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Fusion Negative Regulation Of Cellular Metabolic Process Developmental Process Multicellular Organismal Development Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Positive Regulation Of Late Endosome To Lysosome Transport Pronuclear Fusion Nervous System Development Vesicle Fusion Synaptic Vesicle Exocytosis Negative Regulation Of Biosynthetic Process Negative Regulation Of MRNA 3'-end Processing Central Nervous System Development Regulation Of Glial Cell Differentiation Terminal Button Organization Autophagic Vacuole Maturation Negative Regulation Of Translation	Negative Regulation Of Calcium Ion Transport Negative Regulation Of Ion Transmembrane Transport Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Negative Regulation Of Transmembrane Transport Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of High Voltage-gated Calcium Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ion Transport Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Mitotic Cell Cycle Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Nitric-oxide Synthase Activity Glycogen Catabolic Process Negative Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Dephosphorylation Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Cellular Localization Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Protein Autophosphorylation Regulation Of Calcium Ion Transport Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Adenylate Cyclase Activity Substantia Nigra Development Regulation Of Nitric-oxide Synthase Activity Response To Mineralocorticoid Positive Regulation Of Oxidoreductase Activity Negative Regulation Of Transporter Activity Positive Regulation Of Lyase Activity
Tagcloud ?		aligned amenable avenues baz2a bioinformatic candidates cdk13 chem dapk1 digest dilution dst exosc3 hdms hierarchical inhbe kat2b kif20b linkages noninvasive pancreatic proteomics resectable silva smc1b synapt tryptic unsupervised urgent
Tagcloud (Difference) ?		aligned amenable avenues baz2a bioinformatic candidates cdk13 chem dapk1 digest dilution dst exosc3 hdms hierarchical inhbe kat2b kif20b linkages noninvasive pancreatic proteomics resectable silva smc1b synapt tryptic unsupervised urgent
Tagcloud (Intersection) ?