CXorf66 and STX10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CXorf66	STX10
Description		chromosome X open reading frame 66	syntaxin 10
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Endomembrane System Membrane Synaptic Vesicle Membrane Organelle Membrane SNARE Complex Vesicle Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process		Intracellular Protein Transport Vesicle Fusion Protein Transport Vesicle-mediated Transport Regulation Of Protein Localization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Venous thromboembolism ( 31420334)
Interacting Genes		12 interacting genes: AQP6 ASPH EMD ERGIC3 LAT POMGNT1 RPRM RTP2 STX10 TMEM31 TMX2 YIPF6	6 interacting genes: COQ8A CXorf66 STX1A STX4 TMEM101 USP2-AS1
Entrez ID		347487	8677
HPRD ID		18139	04791
Ensembl ID		ENSG00000203933	ENSG00000104915
Uniprot IDs		Q5JRM2	O60499 Q5U8S2 X6R2W0
PDB IDs			4DND
Enriched GO Terms of Interacting Partners?		Membrane Cortical Endoplasmic Reticulum Positive Regulation Of Intracellular Protein Transport Regulation Of Intracellular Protein Transport Positive Regulation Of Intracellular Transport COPII-coated ER To Golgi Transport Vesicle PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Peptidyl-aspartic Acid 3-dioxygenase Activity Regulation Of Intracellular Transport Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Transport TMEM240-body Golgi Membrane Golgi Apparatus Golgi Vesicle Transport TCR Signalosome Retrograde Transporter Complex, Golgi To ER Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,3-N-acetylglucosaminyltransferase Activity Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Endoplasmic Reticulum Detection Of Chemical Stimulus Regulation Of Protein Localization Cellular Localization Transporter Complex Olfactory Receptor Binding Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Activation Of Store-operated Calcium Channel Activity Positive Regulation Of Protein Localization Regulation Of Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Localization Of Cell Positive Regulation Of Store-operated Calcium Channel Activity Reactive Gliosis	SNARE Complex Assembly SNARE Complex Positive Regulation Of Regulated Secretory Pathway SNAP Receptor Activity SNARE Binding Vesicle Docking Schaffer Collateral - CA1 Synapse Membrane Docking Neurotransmitter Transport Positive Regulation Of Exocytosis Vesicle Fusion Myosin Head/neck Binding Organelle Localization By Membrane Tethering Sphingomyelin Phosphodiesterase Activator Activity Organelle Membrane Fusion Positive Regulation Of Eosinophil Degranulation Storage Vacuole Positive Regulation Of Synaptic Transmission Organelle Fusion Positive Regulation Of Norepinephrine Secretion Regulation Of Regulated Secretory Pathway Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Neuron Projection Membrane Membrane Fusion Regulation Of Insulin Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Lateral Loop Regulation Of Exocytosis Regulation Of Peptide Hormone Secretion Exocytosis Cornified Envelope Assembly Myelin Sheath Adaxonal Region Extrinsic Component Of Mitochondrial Inner Membrane ATP-dependent Protein Binding Response To Gravity Chloride Channel Inhibitor Activity Actomyosin Regulation Of Hormone Secretion Regulation Of Protein Secretion Endomembrane System Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Regulation Of Norepinephrine Secretion Positive Regulation Of Catecholamine Secretion Positive Regulation Of Secretion By Cell Vesicle Organization Positive Regulation Of Secretion Calcium Channel Inhibitor Activity Specific Granule
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