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CELA1 and PI3
Number of citations of the paper that reports this interaction (PubMedID
8794736
)
0
Data Source:
HPRD
(in vivo)
CELA1
PI3
Description
chymotrypsin like elastase 1
peptidase inhibitor 3
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cornified Envelope
Extracellular Region
Extracellular Space
Cytosol
Extracellular Matrix
Molecular Function
Serine-type Endopeptidase Activity
Peptidase Activity
Serine-type Peptidase Activity
Hydrolase Activity
Metal Ion Binding
Endopeptidase Inhibitor Activity
Serine-type Endopeptidase Inhibitor Activity
Structural Constituent Of Skin Epidermis
Peptidase Inhibitor Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Proteolysis
Inflammatory Response
Post-embryonic Development
Wnt Signaling Pathway
Exocrine Pancreas Development
Multicellular Organism Growth
Regulation Of Cell Population Proliferation
Regulation Of Cell Differentiation
Positive Regulation Of Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Tissue Remodeling
Digestive System Development
Elastin Catabolic Process
Pancreas Morphogenesis
Copulation
Peptide Cross-linking
Antibacterial Humoral Response
Innate Immune Response
Pathways
Antimicrobial peptides
Formation of the cornified envelope
Drugs
N,N-dimethylformamide
Cumidine
Mdl 101,146
2-[5-Methanesulfonylamino-2-(4-Aminophenyl)-6-Oxo-1,6-Dihydro-1-Pyrimidinyl]-N-(3,3,3-Trifluoro-1-Isopropyl-2-Oxopropyl)Acetamide
N-{4-[(Carboxymethyl)carbamoyl]benzoyl}-L-valyl-N-[(3S)-1,1,1-trifluoro-4-methyl-2-oxo-3-pentanyl]-L-prolinamide
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-alanyl-L-alaninamide
N-[2-(1-Formyl-2-Methyl-Propyl)-1-(4-Piperidin-1-Yl-but-2-Enoyl)-Pyrrolidin-3-Yl]-Methanesulfonamide
Freselestat
(3R)-3-ethyl-N-[(4-methylphenyl)sulfonyl]-L-aspartic acid
(TERT-BUTYLOXYCARBONYL)-ALANYL-AMINO ETHYL-FORMAMIDE
(2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATE
[1-(3-CHLORO-2-FORMYL-PHENYLCARBAMOYL)-2-METHYL-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTER
METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE
(2R)-3-{[(BENZYLAMINO)CARBONYL]AMINO}-2-HYDROXYPROPANOIC ACID
3-[[(METHYLAMINO)SULFONYL]AMINO]-2-OXO-6-PHENYL-N-[3,3,3-TRIFLUORO-1-(1-METHYLETHYL)-2-OXOPHENYL]-1(2H)-PYRIDINE ACETAMIDE
(2S,3S)-3-FORMYL-2-({[(4-METHYLPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID
(2S,3S)-3-FORMYL-2-({[(4-NITROPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID
Diseases
GWAS
Neutrophil count (
32888494
)
Obesity-related traits (
23251661
)
Bipolar disorder (
31043756
)
Blood protein levels (
30072576
)
Malaria (
31844061
)
Interacting Genes
6 interacting genes:
A2M
CSN2
LPA
PI3
SERPINA1
SERPINA3
5 interacting genes:
CELA1
CSTA
EVPL
KRT1
LORICRIN
Entrez ID
1990
5266
HPRD ID
00553
15947
Ensembl ID
ENSG00000139610
ENSG00000124102
Uniprot IDs
Q9UNI1
P19957
PDB IDs
1FLE
2REL
6ATU
Enriched GO Terms of Interacting Partners
?
Serine-type Endopeptidase Inhibitor Activity
Peptidase Inhibitor Activity
Endopeptidase Inhibitor Activity
Extracellular Region
Platelet Alpha Granule Lumen
Extracellular Space
Extracellular Matrix
Acute-phase Response
Growth Factor Binding
Acute Inflammatory Response
Plasma Lipoprotein Particle
Negative Regulation Of Complement Activation, Lectin Pathway
Y Chromosome
Positive Regulation Of Heterochromatin Formation
Cyclin A1-CDK2 Complex
Cyclin E2-CDK2 Complex
Positive Regulation Of DNA-templated DNA Replication Initiation
Positive Regulation Of Cardiac Muscle Tissue Development
ERBB3:ERBB2 Complex
Copulation
Protease Binding
Interleukin-8 Binding
Blood Microparticle
Positive Regulation Of Chromatin Organization
Cyclin-dependent Protein Kinase Activity
Cyclin A2-CDK2 Complex
Cyclin E1-CDK2 Complex
Neuregulin Receptor Activity
X Chromosome
ErbB-3 Class Receptor Binding
Neuregulin Binding
Regulation Of Cardiac Muscle Tissue Development
Regulation Of Anaphase-promoting Complex-dependent Catabolic Process
Histone Kinase Activity
Tumor Necrosis Factor Binding
Interleukin-1 Binding
Protection From Non-homologous End Joining At Telomere
Schwann Cell Differentiation
Regulation Of Heterochromatin Formation
ERBB2-ERBB3 Signaling Pathway
ERBB3 Signaling Pathway
Peptide Cross-linking
Cornified Envelope
Keratinocyte Differentiation
Keratinization
Epidermal Cell Differentiation
Protein Metabolic Process
Protein Modification Process
Cytoskeleton Organization
Structural Constituent Of Skin Epidermis
Epithelial Cell Differentiation
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Macromolecule Metabolic Process
Developmental Process
Elastin Catabolic Process
Pancreas Morphogenesis
Epidermis Development
Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Intermediate Filament
Peptidase Inhibitor Complex
Cellular Response To Progesterone Stimulus
Elastin Metabolic Process
Regulation Of Anatomical Structure Morphogenesis
Regulation Of Antibacterial Peptide Production
Regulation Of Defense Response
Negative Regulation Of Inflammatory Response
Negative Regulation Of Neutrophil Activation
Regulation Of Caveolin-mediated Endocytosis
Connexin Binding
Positive Regulation Of Dephosphorylation
Osteoclast Development
Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Positive Regulation Of Lamellipodium Morphogenesis
Signal Complex Assembly
Negative Regulation Of Mitochondrial Depolarization
Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Signaling Receptor Activator Activity
Cell Differentiation
Exocrine Pancreas Development
Digestive System Development
Regulation Of Antimicrobial Humoral Response
Regulation Of Immune Response
Complement Activation, Lectin Pathway
Negative Regulation Of Defense Response
Regulation Of Toll-like Receptor 3 Signaling Pathway
Regulation Of Lamellipodium Morphogenesis
Intestinal Epithelial Cell Development
Positive Regulation Of Podosome Assembly
Positive Regulation Of Integrin Activation
Phospholipase Activator Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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