EIF4G2 and C1QTNF9

Number of citations: 48 (PubMedID 23414517)
Data Source: BioGRID (two hybrid)

		EIF4G2	C1QTNF9
Name		eukaryotic translation initiation factor 4 gamma 2	C1q and TNF related 9
Structure			No pdb structure
GO Annotations	Cellular Component	Cytosol Adherens Junction Membrane Eukaryotic Translation Initiation Factor 4F Complex	Extracellular Region Collagen Trimer
	Molecular Function	RNA Binding MRNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Cadherin Binding	Hormone Activity Protein Binding Identical Protein Binding
	Biological Process	Translation Translational Initiation Regulation Of Translation Regulation Of Translational Initiation Cell Death Negative Regulation Of Autophagy Positive Regulation Of Cell Growth Regulation Of Cell Cycle	Signal Transduction
Pathways		ISG15 antiviral mechanism	None
GWAS		Metabolite levels ( 23823483 )	No GWAS studies recorded
Interacting Genes		18 interacting genes: C1QTNF9 CASP3 CEBPA CREBBP EIF2S2 EIF3A EIF4A1 EIF4A2 EIF4E EIF5 LCOR MKNK1 NCBP1 OGT RNF10 SKIL SUMO2 TTC3	17 interacting genes: ACTC1 AMPD1 APPL1 CAPN3 DENND4A DST EIF4G2 GYG1 LARP4B MYBPC1 MYOM1 NAP1L1 NDUFS1 RDX TTN UTRN ZNF407
Entrez ID		1982	338872
HPRD ID		09084	14659
Ensembl ID		ENSG00000110321	ENSG00000240654
Uniprot IDs		P78344 Q2TU89	P0C862
PDB IDs		3D3M 3L6A 4IUL 9JJ7	Not available
GO Terms Enriched among Interactors		Translational Initiation Translation Initiation Factor Activity Cytoplasmic Translational Initiation Translation RNA Cap Binding Eukaryotic Translation Initiation Factor 4F Complex Macromolecule Metabolic Process Macromolecule Biosynthetic Process Protein Metabolic Process Chromatin DNA Binding Regulation Of Gene Expression Regulation Of Translation Regulation Of Translational Initiation Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Protein Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Post-transcriptional Regulation Of Gene Expression Protein-RNA Complex Assembly RNA 7-methylguanosine Cap Binding Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Formation Of Cytoplasmic Translation Initiation Complex RNA Binding MRNA Binding Nucleoplasm Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Translation Factor Activity, RNA Binding Glutamatergic Synapse Negative Regulation Of Biosynthetic Process Histone Acetyltransferase Complex Response To Glucocorticoid Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Organization Response To Corticosteroid Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Pyroptotic Inflammatory Response DNA-binding Transcription Factor Binding RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Dexamethasone Negative Regulation Of RNA-dependent RNA Polymerase Activity Eukaryotic Initiation Factor 4G Binding	Actomyosin Structure Organization Structural Constituent Of Muscle Sarcomere Organization Protein Kinase A Signaling M Band Myofibril Assembly Skeletal Muscle Thin Filament Assembly Actin Cytoskeleton Organization Actin Filament-based Process Filopodium Titin Binding Cardiac Myofibril Assembly Actin-myosin Filament Sliding Actin Cytoskeleton Myosin Filament Muscle Organ Development Cytoskeleton Organization I Band Myosin Binding Z Disc Muscle Structure Development Actin Binding Protein Homodimerization Activity Actin-mediated Cell Contraction Structural Molecule Activity Positive Regulation Of Gene Expression Muscle Contraction Cardiac Muscle Contraction Cytosol Calcium-dependent Self Proteolysis Positive Regulation Of Transport Myofibril T-tubule Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Sarcomere Muscle System Process Actin Filament-based Movement Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process H Zone Ligase Regulator Activity Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Glycogenin Glucosyltransferase Activity Titin-telethonin Complex Structural Molecule Activity Conferring Elasticity Sarcomerogenesis Positive Regulation Of Macropinocytosis Cytoskeletal Protein Binding Positive Regulation Of Biosynthetic Process Muscle Tissue Morphogenesis