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C1QTNF9 and NDUFS1
Number of citations of the paper that reports this interaction (PubMedID
23414517
)
48
Data Source:
BioGRID
(two hybrid)
C1QTNF9
NDUFS1
Description
C1q and TNF related 9
NADH:ubiquinone oxidoreductase core subunit S1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Collagen Trimer
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Intermembrane Space
Mitochondrial Matrix
Membrane
Respiratory Chain Complex I
Molecular Function
Hormone Activity
Protein Binding
Identical Protein Binding
Protein Binding
NADH Dehydrogenase (ubiquinone) Activity
Electron Transfer Activity
Oxidoreductase Activity
Oxidoreductase Activity, Acting On NAD(P)H
Metal Ion Binding
Iron-sulfur Cluster Binding
2 Iron, 2 Sulfur Cluster Binding
4 Iron, 4 Sulfur Cluster Binding
Biological Process
Signal Transduction
Mitochondrial Electron Transport, NADH To Ubiquinone
Aerobic Respiration
Mitochondrial Respiratory Chain Complex I Assembly
ATP Synthesis Coupled Electron Transport
Proton Motive Force-driven Mitochondrial ATP Synthesis
Cellular Respiration
Proton Transmembrane Transport
Pathways
Respiratory electron transport
Complex I biogenesis
Mitochondrial protein degradation
Drugs
NADH
Diseases
Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Body mass index (
26426971
)
Chronotype (
30696823
)
Daytime nap (
33568662
)
Frontotemporal dementia with GRN mutation (
29724592
)
Morning person (
30696823
)
Interacting Genes
17 interacting genes:
ACTC1
AMPD1
APPL1
CAPN3
DENND4A
DST
EIF4G2
GYG1
LARP4B
MYBPC1
MYOM1
NAP1L1
NDUFS1
RDX
TTN
UTRN
ZNF407
5 interacting genes:
C1QTNF9
CASP3
KDM1A
MDH2
MDM2
Entrez ID
338872
4719
HPRD ID
14659
01145
Ensembl ID
ENSG00000240654
ENSG00000023228
Uniprot IDs
P0C862
E5KRK5
P28331
PDB IDs
5XTB
5XTD
5XTH
5XTI
Enriched GO Terms of Interacting Partners
?
Actomyosin Structure Organization
Structural Constituent Of Muscle
Sarcomere Organization
Protein Kinase A Signaling
M Band
Myofibril Assembly
Skeletal Muscle Thin Filament Assembly
Actin Cytoskeleton Organization
Actin Filament-based Process
Filopodium
Titin Binding
Cardiac Myofibril Assembly
Actin-myosin Filament Sliding
Actin Cytoskeleton
Myosin Filament
Muscle Organ Development
Cytoskeleton Organization
I Band
Myosin Binding
Z Disc
Muscle Structure Development
Actin Binding
Protein Homodimerization Activity
Actin-mediated Cell Contraction
Structural Molecule Activity
Positive Regulation Of Gene Expression
Muscle Contraction
Cardiac Muscle Contraction
Cytosol
Calcium-dependent Self Proteolysis
Positive Regulation Of Transport
Myofibril
T-tubule
Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Sarcomere
Muscle System Process
Actin Filament-based Movement
Cardiac Muscle Tissue Morphogenesis
Positive Regulation Of Macromolecule Biosynthetic Process
H Zone
Ligase Regulator Activity
Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration
Glycogenin Glucosyltransferase Activity
Titin-telethonin Complex
Structural Molecule Activity Conferring Elasticity
Sarcomerogenesis
Positive Regulation Of Macropinocytosis
Cytoskeletal Protein Binding
Positive Regulation Of Biosynthetic Process
Muscle Tissue Morphogenesis
Death-inducing Signaling Complex
Death Receptor Binding
Response To Ionizing Radiation
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Response To UV
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Cellular Response To Gamma Radiation
Cellular Response To Alkaloid
Response To Steroid Hormone
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Negative Regulation Of Apoptotic Signaling Pathway
Response To Antibiotic
Heart Development
Negative Regulation Of Signal Transduction By P53 Class Mediator
Response To Hypoxia
Response To Decreased Oxygen Levels
Response To Light Stimulus
Response To Gamma Radiation
Response To Oxygen Levels
Cysteine-type Endopeptidase Activity
Positive Regulation Of Neuron Apoptotic Process
L-malate Dehydrogenase (NADP+) Activity
P53 Binding
Cellular Response To Ionizing Radiation
Response To Formaldehyde
Cellular Response To Vitamin B1
Regulation Of Apoptotic Signaling Pathway
Enzyme Activator Activity
Response To Alkaloid
Response To Radiation
Cellular Response To UV
Regulation Of Neuron Projection Development
Protease Binding
Response To Hydrogen Peroxide
Phospholipase A2 Activator Activity
Cellular Response To Light Stimulus
Response To Toxic Substance
Skeletal Myofibril Assembly
Telomeric Repeat-containing RNA Binding
FAD-dependent H3K4me/H3K4me3 Demethylase Activity
Response To Estradiol
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress
Cysteine-type Peptidase Activity
Response To Glucocorticoid
L-malate Dehydrogenase (NAD+) Activity
Malate Dehydrogenase Activity
Response To Vitamin B1
Response To Water-immersion Restraint Stress
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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