TOR1A and TOR1AIP1

Number of citations of the paper that reports this interaction (PMID 23569223)
7

Data Source:
BioGRID (pull down)

		TOR1A	TOR1AIP1
Gene Name		torsin family 1, member A (torsin A)	torsin A interacting protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Lumen Cytoskeleton Synaptic Vesicle Membrane Cell Junction Transport Vesicle Secretory Granule Growth Cone Cytoplasmic Vesicle Membrane Nuclear Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Nucleus Nuclear Inner Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding ATP Binding Cytoskeletal Protein Binding ATPase Activity Kinesin Binding Unfolded Protein Binding Misfolded Protein Binding	ATPase Activator Activity Lamin Binding Cytoskeletal Protein Binding ATPase Binding
	Biological Process	Protein Deneddylation Response To Oxidative Stress Organelle Organization Nuclear Envelope Organization Cell Adhesion Neuron Projection Development Protein Localization To Nucleus Wound Healing, Spreading Of Cells Intermediate Filament Cytoskeleton Organization Synaptic Vesicle Transport Chaperone Mediated Protein Folding Requiring Cofactor Protein Homooligomerization Regulation Of Dopamine Uptake Involved In Synaptic Transmission Chaperone-mediated Protein Folding ER-associated Misfolded Protein Catabolic Process Nuclear Membrane Organization Chaperone-mediated Protein Transport Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Protein Localization To Cell Surface	Positive Regulation Of ATPase Activity Protein Localization To Nucleus Nuclear Membrane Organization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: KRTAP10-7 LMNA LRRC7 SNCA TOR1AIP1 TOR1AIP2 TOR1B	7 interactors: LMNA LMNB1 PPP1CA PPP1CC TERF2 TERF2IP TOR1A
Entrez ID		1861	26092
HPRD ID		06897	13958
Ensembl ID		ENSG00000136827	ENSG00000143337
Uniprot IDs		B3KPA1 O14656	Q5JTV8
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Envelope Organization Nuclear Membrane Organization Endomembrane System Organization Nucleus Organization Membrane Organization Positive Regulation Of ATPase Activity Positive Regulation Of Hydrolase Activity Regulation Of ATPase Activity Endoplasmic Reticulum Organization Organelle Organization Positive Regulation Of Catalytic Activity Negative Regulation Of Thrombin Receptor Signaling Pathway Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Sterol Regulatory Element Binding Protein Import Into Nucleus Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Response To Unfolded Protein Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of Catalytic Activity Protein Localization To Nucleus Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Cellular Respiration Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Negative Regulation Of Oxidative Phosphorylation Negative Regulation Of Synaptic Transmission, Dopaminergic Response To Iron(II) Ion Cellular Response To Copper Ion Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Cell Aging Regulation Of Dopamine Uptake Involved In Synaptic Transmission Mitotic Nuclear Envelope Reassembly Positive Regulation Of Metabolic Process Regulation Of Oxidative Phosphorylation Positive Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Hydrogen Peroxide Metabolic Process Dopamine Transport Nuclear Envelope Reassembly Regulation Of Glutamate Secretion Dopamine Biosynthetic Process Negative Regulation Of Monooxygenase Activity Neurotransmitter Uptake Regulation Of Cellular Respiration Microglial Cell Activation Extracellular Fibril Organization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Synaptic Transmission, Dopaminergic SREBP Signaling Pathway	Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Protein Localization To Organelle Regulation Of Telomere Maintenance Triglyceride Catabolic Process RNA-dependent DNA Replication Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening Glycogen Metabolic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Nuclear Envelope Organization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Execution Phase Of Apoptosis Telomere Maintenance Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Negative Regulation Of Chromosome Organization Sterol Regulatory Element Binding Protein Import Into Nucleus Negative Regulation Of DNA Recombination At Telomere Cell Cycle Cellular Protein Localization Triglyceride Metabolic Process Regulation Of Circadian Rhythm Negative Regulation Of DNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Topologically Incorrect Protein Cellular Response To Stress Nucleus Organization Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Signaling Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Lipid Catabolic Process Telomeric Loop Formation Positive Regulation Of Synaptic Vesicle Endocytosis Age-dependent Telomere Shortening ER-associated Misfolded Protein Catabolic Process Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Protein Localization To Nucleus Circadian Rhythm
Tagcloud ?		circuits cns cre deltae discrete disrupts dystonia dystonic dyt1 envelope flox hrd1 hypofunction lumen milder movements nestin neurodegeneration neurodevelopmental overtly perinuclear raise reticular sensorimotor striking stymied torsina twisting underpinnings	dephosphorylated dreifuss dystonia dystrophy dyt1 emerin emery envelope integral isoform isoforms lamina lamins lap1 lap1a lap1b lap1c methionine muscular originate permitted pp1 putatively silico torsina translationally ubiquitously undergoes unraveled
Tagcloud (Difference) ?		circuits cns cre deltae discrete disrupts dystonic flox hrd1 hypofunction lumen milder movements nestin neurodegeneration neurodevelopmental overtly perinuclear raise reticular sensorimotor striking stymied twisting underpinnings	dephosphorylated dreifuss dystrophy emerin emery integral isoform isoforms lamina lamins lap1 lap1a lap1b lap1c methionine muscular originate permitted pp1 putatively silico translationally ubiquitously undergoes unraveled
Tagcloud (Intersection) ?		dystonia dyt1 envelope torsina