TOR1A and TOR1AIP2

Number of citations of the paper that reports this interaction (PMID 15767459)
42

Data Source:
HPRD (in vivo)

		TOR1A	TOR1AIP2
Gene Name		torsin family 1, member A (torsin A)	torsin A interacting protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Lumen Cytoskeleton Synaptic Vesicle Membrane Cell Junction Transport Vesicle Secretory Granule Growth Cone Cytoplasmic Vesicle Membrane Nuclear Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Nuclear Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding ATP Binding Cytoskeletal Protein Binding ATPase Activity Kinesin Binding Unfolded Protein Binding Misfolded Protein Binding	ATPase Activator Activity ATPase Binding
	Biological Process	Protein Deneddylation Response To Oxidative Stress Organelle Organization Nuclear Envelope Organization Cell Adhesion Neuron Projection Development Protein Localization To Nucleus Wound Healing, Spreading Of Cells Intermediate Filament Cytoskeleton Organization Synaptic Vesicle Transport Chaperone Mediated Protein Folding Requiring Cofactor Protein Homooligomerization Regulation Of Dopamine Uptake Involved In Synaptic Transmission Chaperone-mediated Protein Folding ER-associated Misfolded Protein Catabolic Process Nuclear Membrane Organization Chaperone-mediated Protein Transport Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Protein Localization To Cell Surface	Endoplasmic Reticulum Organization Positive Regulation Of ATPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: KRTAP10-7 LMNA LRRC7 SNCA TOR1AIP1 TOR1AIP2 TOR1B	2 interactors: RBPMS TOR1A
Entrez ID		1861	163590
HPRD ID		06897	10048
Ensembl ID		ENSG00000136827	ENSG00000169905
Uniprot IDs		B3KPA1 O14656	Q8NFQ8 Q9H496
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Envelope Organization Nuclear Membrane Organization Endomembrane System Organization Nucleus Organization Membrane Organization Positive Regulation Of ATPase Activity Positive Regulation Of Hydrolase Activity Regulation Of ATPase Activity Endoplasmic Reticulum Organization Organelle Organization Positive Regulation Of Catalytic Activity Negative Regulation Of Thrombin Receptor Signaling Pathway Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Sterol Regulatory Element Binding Protein Import Into Nucleus Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Response To Unfolded Protein Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of Catalytic Activity Protein Localization To Nucleus Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Cellular Respiration Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Negative Regulation Of Oxidative Phosphorylation Negative Regulation Of Synaptic Transmission, Dopaminergic Response To Iron(II) Ion Cellular Response To Copper Ion Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Cell Aging Regulation Of Dopamine Uptake Involved In Synaptic Transmission Mitotic Nuclear Envelope Reassembly Positive Regulation Of Metabolic Process Regulation Of Oxidative Phosphorylation Positive Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Hydrogen Peroxide Metabolic Process Dopamine Transport Nuclear Envelope Reassembly Regulation Of Glutamate Secretion Dopamine Biosynthetic Process Negative Regulation Of Monooxygenase Activity Neurotransmitter Uptake Regulation Of Cellular Respiration Microglial Cell Activation Extracellular Fibril Organization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Synaptic Transmission, Dopaminergic SREBP Signaling Pathway	Positive Regulation Of Synaptic Vesicle Endocytosis ER-associated Misfolded Protein Catabolic Process Nuclear Membrane Organization Regulation Of Synaptic Vesicle Endocytosis Regulation Of Synaptic Vesicle Recycling Chaperone-mediated Protein Transport Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Deneddylation Positive Regulation Of Transport Regulation Of Protein Localization Positive Regulation Of SMAD Protein Import Into Nucleus Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Regulation Of Neurotransmitter Uptake Response To Misfolded Protein Regulation Of SMAD Protein Import Into Nucleus Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Protein Localization To Cell Surface Regulation Of Cellular Localization Chaperone Mediated Protein Folding Requiring Cofactor Wound Healing, Spreading Of Cells ER-associated Ubiquitin-dependent Protein Catabolic Process Intermediate Filament Cytoskeleton Organization Regulation Of Synaptic Vesicle Transport Intermediate Filament-based Process Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Morphogenesis Of An Epithelial Sheet Chaperone-mediated Protein Folding Nuclear Envelope Organization Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Endocytosis Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Synaptic Vesicle Transport Cellular Response To Topologically Incorrect Protein Positive Regulation Of Synaptic Transmission Protein Modification By Small Protein Removal Nucleus Organization Regulation Of Anion Transport Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Protein Localization To Nucleus
Tagcloud ?		circuits cns cre deltae discrete disrupts dystonia dystonic dyt1 envelope flox hrd1 hypofunction lumen milder movements nestin neurodegeneration neurodevelopmental overtly perinuclear raise reticular sensorimotor striking stymied torsina twisting underpinnings
Tagcloud (Difference) ?		circuits cns cre deltae discrete disrupts dystonia dystonic dyt1 envelope flox hrd1 hypofunction lumen milder movements nestin neurodegeneration neurodevelopmental overtly perinuclear raise reticular sensorimotor striking stymied torsina twisting underpinnings
Tagcloud (Intersection) ?