DSC2 and PKP3

Number of citations of the paper that reports this interaction (PMID 12707304)
37

Data Source:
HPRD (two hybrid)

		DSC2	PKP3
Gene Name		desmocollin 2	plakophilin 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell-cell Adherens Junction Intercalated Disc Integral Component Of Membrane Desmosome Cytoplasmic Vesicle Extracellular Vesicular Exosome	Nucleus Plasma Membrane Cell-cell Junction Desmosome
	Molecular Function	Calcium Ion Binding Protein Binding	Cell Adhesion Molecule Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cellular Response To Starvation Ventricular Cardiac Muscle Cell Action Potential Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Heart Rate By Cardiac Conduction	Desmosome Assembly Single Organismal Cell-cell Adhesion Establishment Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: DSG1 DSG2 JUP PKP2 PKP3	9 interactors: DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSP JUP KRT18
Entrez ID		1824	11187
HPRD ID		00512	05711
Ensembl ID		ENSG00000134755	ENSG00000184363
Uniprot IDs		Q02487	F8J390 Q9Y446
PDB IDs
Enriched GO Terms of Interacting Partners?		Desmosome Assembly Bundle Of His Cell To Purkinje Myocyte Communication Desmosome Organization Cell-cell Junction Assembly Ventricular Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Cell Junction Assembly Cell-cell Junction Organization Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Cell Adhesion Regulation Of Striated Muscle Contraction Action Potential Single Organismal Cell-cell Adhesion Regulation Of Muscle Contraction Regulation Of Heart Contraction Regulation Of Membrane Potential Response To Progesterone Regulation Of Actin Filament-based Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Establishment Of Protein Localization To Plasma Membrane Maternal Process Involved In Female Pregnancy Adherens Junction Organization Cellular Component Assembly Regulation Of Cellular Component Movement Protein Localization To Plasma Membrane Response To Organic Cyclic Compound Endothelial Cell-cell Adhesion Adherens Junction Maintenance Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Plasma Membrane Organization Establishment Of Protein Localization To Membrane Cellular Response To Indole-3-methanol Maintenance Of Organ Identity Female Pregnancy Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Intermediate Filament Bundle Assembly Regulation Of Tight Junction Assembly Cytoskeletal Anchoring At Plasma Membrane Protein Localization To Membrane Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cell Communication By Electrical Coupling Endomembrane System Organization Cell-cell Signaling Involved In Cardiac Conduction	Bundle Of His Cell To Purkinje Myocyte Communication Ventricular Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cell Adhesion Regulation Of Muscle Contraction Regulation Of Heart Contraction Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Regulation Of Membrane Potential Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Regulation Of Actin Filament-based Process Single Organismal Cell-cell Adhesion Regulation Of Cellular Component Movement Desmosome Organization Apoptotic Process Programmed Cell Death Cell Death Death Cell-cell Junction Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Response To Progesterone Golgi To Plasma Membrane CFTR Protein Transport Establishment Of Protein Localization To Plasma Membrane Maternal Process Involved In Female Pregnancy Adherens Junction Organization Protein Stabilization Ventricular Compact Myocardium Morphogenesis Cell-cell Junction Assembly Signaling Cell Communication Endothelial Cell-cell Adhesion Regulation Of Protein Stability Cellular Response To Starvation Response To Stimulus Protein Localization To Plasma Membrane Desmosome Assembly Protein Localization To Adherens Junction Cellular Response To Indole-3-methanol
Tagcloud ?		cadherins companion continuity desmocollin desmoglein desmoplakin desmosomal desmosomes displaying dsc1 dsc3 dsg1 dsg2 dsg3 exclusive follicle hair immunopositive mutually ontogenic outer plakoglobin plakophilin practically rood root sheath subinfundibular trichocytes	ankrd33b asthma beadchip cntd2 concordant cpg detrimental dpp10 enrichment epigenome fetal goal gtf2h2c gtf2h2d humanmethylation450 illumina ius lung mapped methylation methylome nicotine origins placental smoke surrogate utero variation wheezing
Tagcloud (Difference) ?		cadherins companion continuity desmocollin desmoglein desmoplakin desmosomal desmosomes displaying dsc1 dsc3 dsg1 dsg2 dsg3 exclusive follicle hair immunopositive mutually ontogenic outer plakoglobin plakophilin practically rood root sheath subinfundibular trichocytes	ankrd33b asthma beadchip cntd2 concordant cpg detrimental dpp10 enrichment epigenome fetal goal gtf2h2c gtf2h2d humanmethylation450 illumina ius lung mapped methylation methylome nicotine origins placental smoke surrogate utero variation wheezing
Tagcloud (Intersection) ?