DSC2 and DSG2

Number of citations of the paper that reports this interaction (PMID 11853539)
26

Data Source:
HPRD (in vitro)

		DSC2	DSG2
Gene Name		desmocollin 2	desmoglein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell-cell Adherens Junction Intercalated Disc Integral Component Of Membrane Desmosome Cytoplasmic Vesicle Extracellular Vesicular Exosome	Plasma Membrane Cell-cell Junction Cell Surface Integral Component Of Membrane Apical Plasma Membrane Lateral Plasma Membrane Desmosome Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding	Calcium Ion Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cellular Response To Starvation Ventricular Cardiac Muscle Cell Action Potential Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Heart Rate By Cardiac Conduction	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Response To Progesterone Maternal Process Involved In Female Pregnancy Ventricular Cardiac Muscle Cell Action Potential Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Heart Rate By Cardiac Conduction
Pathways			Apoptotic cleavage of cell adhesion proteins Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: DSG1 DSG2 JUP PKP2 PKP3	5 interactors: DSC1 DSC2 JUP PKP2 PKP3
Entrez ID		1824	1829
HPRD ID		00512	00516
Ensembl ID		ENSG00000134755	ENSG00000046604
Uniprot IDs		Q02487	Q14126
PDB IDs			2YQG
Enriched GO Terms of Interacting Partners?		Desmosome Assembly Bundle Of His Cell To Purkinje Myocyte Communication Desmosome Organization Cell-cell Junction Assembly Ventricular Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Cell Junction Assembly Cell-cell Junction Organization Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Cell Adhesion Regulation Of Striated Muscle Contraction Action Potential Single Organismal Cell-cell Adhesion Regulation Of Muscle Contraction Regulation Of Heart Contraction Regulation Of Membrane Potential Response To Progesterone Regulation Of Actin Filament-based Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Establishment Of Protein Localization To Plasma Membrane Maternal Process Involved In Female Pregnancy Adherens Junction Organization Cellular Component Assembly Regulation Of Cellular Component Movement Protein Localization To Plasma Membrane Response To Organic Cyclic Compound Endothelial Cell-cell Adhesion Adherens Junction Maintenance Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Plasma Membrane Organization Establishment Of Protein Localization To Membrane Cellular Response To Indole-3-methanol Maintenance Of Organ Identity Female Pregnancy Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Intermediate Filament Bundle Assembly Regulation Of Tight Junction Assembly Cytoskeletal Anchoring At Plasma Membrane Protein Localization To Membrane Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cell Communication By Electrical Coupling Endomembrane System Organization Cell-cell Signaling Involved In Cardiac Conduction	Desmosome Assembly Bundle Of His Cell To Purkinje Myocyte Communication Desmosome Organization Ventricular Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Cell Adhesion Regulation Of Striated Muscle Contraction Action Potential Cell-cell Junction Assembly Single Organismal Cell-cell Adhesion Regulation Of Muscle Contraction Regulation Of Heart Contraction Cell Junction Assembly Cell-cell Junction Organization Regulation Of Membrane Potential Regulation Of Actin Filament-based Process Establishment Of Protein Localization To Plasma Membrane Adherens Junction Organization Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Regulation Of Cellular Component Movement Protein Localization To Plasma Membrane Endothelial Cell-cell Adhesion Adherens Junction Maintenance Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Plasma Membrane Organization Establishment Of Protein Localization To Membrane Cellular Response To Indole-3-methanol Maintenance Of Organ Identity Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Intermediate Filament Bundle Assembly Regulation Of Tight Junction Assembly Cytoskeletal Anchoring At Plasma Membrane Protein Localization To Membrane Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cell Communication By Electrical Coupling Endomembrane System Organization Cell-cell Signaling Involved In Cardiac Conduction Intermediate Filament Organization Regulation Of Cell Fate Specification Cellular Component Assembly Gap Junction Assembly Cellular Component Maintenance Regulation Of Cell Fate Commitment
Tagcloud ?		cadherins companion continuity desmocollin desmoglein desmoplakin desmosomal desmosomes displaying dsc1 dsc3 dsg1 dsg2 dsg3 exclusive follicle hair immunopositive mutually ontogenic outer plakoglobin plakophilin practically rood root sheath subinfundibular trichocytes	cadherins companion continuity desmocollin desmoglein desmoplakin desmosomal desmosomes displaying dsc1 dsc2 dsc3 dsg1 dsg3 exclusive follicle hair immunopositive mutually ontogenic outer plakoglobin plakophilin practically rood root sheath subinfundibular trichocytes
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		cadherins companion continuity desmocollin desmoglein desmoplakin desmosomal desmosomes displaying dsc1 dsc2 dsc3 dsg1 dsg2 dsg3 exclusive follicle hair immunopositive mutually ontogenic outer plakoglobin plakophilin practically rood root sheath subinfundibular trichocytes