PRX

Description		periaxin
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GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Anchoring Junction
	Molecular Function	Protein Binding
	Biological Process	Axon Ensheathment Peripheral Nervous System Myelin Maintenance Regulation Of RNA Splicing
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)
Interacting Genes		3 interacting genes: CDK6 DRP2 TERF2IP
Entrez ID		57716
HPRD ID		05758
Ensembl ID		ENSG00000105227
Uniprot IDs		A0A669KBF1 Q9BXM0
PDB IDs		4CMZ
Enriched GO Terms of Interacting Partners?		Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex Cyclin D2-CDK6 Complex FBXO Family Protein Binding Negative Regulation Of DNA Recombination At Telomere Gliogenesis Negative Regulation Of Monocyte Differentiation Cell Dedifferentiation Shelterin Complex Protection From Non-homologous End Joining At Telomere Nuclear Telomere Cap Complex Type B Pancreatic Cell Development Protein Localization To Chromosome, Telomeric Region Telomere Capping G-rich Strand Telomeric DNA Binding Lateral Ventricle Development Telomere Maintenance In Response To DNA Damage Regulation Of Hematopoietic Stem Cell Differentiation Astrocyte Development Regulation Of Monocyte Differentiation Generation Of Neurons Hematopoietic Stem Cell Differentiation Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Senescence RNA-templated DNA Biosynthetic Process Dentate Gyrus Development Cyclin-dependent Protein Serine/threonine Kinase Activity Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Nuclear Chromosome Cyclin Binding
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